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Clinical Trials/NCT04242316
NCT04242316
Completed
N/A

Effects of Mirror Therapy and Bilateral Arm Training on Hemiparetic Upper Extremity in Patients With Chronic Stroke

The Hong Kong Polytechnic University0 sites101 target enrollmentJanuary 1, 2014

Overview

Phase
N/A
Intervention
Not specified
Conditions
Stroke
Sponsor
The Hong Kong Polytechnic University
Enrollment
101
Primary Endpoint
Fugl-Meyer assessment (FMA)
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of this study included (1) to compare the effectiveness of mirror therapy (MT) and bimanual arm training (BAT) in improving motor and functional performance of hemiplegic upper extremity for adults with chronic stroke; (2) to examine whether recruitment of the mirror neurons, as reflected in mu rhythm suppression, mediates recognition of the mirror illusion in pre/post MT, as compared to BAT without a mirror in clients with chronic stroke, as compared to healthy participants.

Detailed Description

Mirror Therapy (MT) appeared to have beneficial effects on the recovery of distal function of the hemiplegic hand in the evidence recently, however, it is not known whether the incongruent visual feedback induced by mirror in bilateral arm training (BAT) is beneficial to the motor performance of upper extremity than without the mirror in patients with chronic stroke. This study aimed to compare the effectiveness of MT and bimanual arm training (BAT) in improving motor and functional performance of hemiplegic upper extremity for adults with chronic stroke. Participants with chronic stroke were recruited by convenience sampling from a convalescent hospital and self-help groups in the community in Hong Kong. Participants were randomly assigned to the MT group or BAT group and participated in a 6-week upper limb training programme which consisted of two 45-minute training sessions per week. Both kinds of training were equivalent to each other except that there was a mirror used in the MT group. Main outcome measures were upper extremity motor and functional tests, and grip strength. Participants were evaluated at baseline, post-treatment and 3-month follow-up. EEG was assessed before and after the training in a group of stroke patients and healthy controls, in order to evaluate the recruitment of the mirror neurons, as reflected in mu rhythm suppression.

Registry
clinicaltrials.gov
Start Date
January 1, 2014
End Date
January 1, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • neurological condition with unilateral hemiparesis;
  • a Functional Test of Hemiplegic Upper Extremity (FTHUE) score between levels 2 to 6;
  • chronic stroke with onset of neurological condition more than 6 months previously;
  • ability to understand and follow simple verbal instructions;
  • ability to participate in a therapy session lasting at least 30 minutes;
  • community ambulant with or without aids.

Exclusion Criteria

  • Individuals with severe neglect and severe spasticity (Modified Ashworth Scale \>3) would be excluded.

Outcomes

Primary Outcomes

Fugl-Meyer assessment (FMA)

Time Frame: 3-month after the completion of training

FMA-UE is a standard upper limb motor impairment assessment for stroke survivors. FMA-UE assesses voluntary movement, reflex activity, grasp and coordination.

Secondary Outcomes

  • Action Research Arm Test (ARAT)(3-month after the completion of training)
  • Wolf Motor Function Test (WMFT)(3-month after the completion of training)

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