跳至主要内容
临床试验/NCT04242316
NCT04242316已完成不适用

Effects of Mirror Therapy and Bilateral Arm Training on Hemiparetic Upper Extremity in Patients With Chronic Stroke

The Hong Kong Polytechnic University0 个研究点目标入组 101 人开始时间: 2014年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
101
主要终点
Fugl-Meyer assessment (FMA)

研究概览

简要总结

The aim of this study included (1) to compare the effectiveness of mirror therapy (MT) and bimanual arm training (BAT) in improving motor and functional performance of hemiplegic upper extremity for adults with chronic stroke; (2) to examine whether recruitment of the mirror neurons, as reflected in mu rhythm suppression, mediates recognition of the mirror illusion in pre/post MT, as compared to BAT without a mirror in clients with chronic stroke, as compared to healthy participants.

详细描述

Mirror Therapy (MT) appeared to have beneficial effects on the recovery of distal function of the hemiplegic hand in the evidence recently, however, it is not known whether the incongruent visual feedback induced by mirror in bilateral arm training (BAT) is beneficial to the motor performance of upper extremity than without the mirror in patients with chronic stroke. This study aimed to compare the effectiveness of MT and bimanual arm training (BAT) in improving motor and functional performance of hemiplegic upper extremity for adults with chronic stroke. Participants with chronic stroke were recruited by convenience sampling from a convalescent hospital and self-help groups in the community in Hong Kong. Participants were randomly assigned to the MT group or BAT group and participated in a 6-week upper limb training programme which consisted of two 45-minute training sessions per week. Both kinds of training were equivalent to each other except that there was a mirror used in the MT group. Main outcome measures were upper extremity motor and functional tests, and grip strength. Participants were evaluated at baseline, post-treatment and 3-month follow-up. EEG was assessed before and after the training in a group of stroke patients and healthy controls, in order to evaluate the recruitment of the mirror neurons, as reflected in mu rhythm suppression.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • neurological condition with unilateral hemiparesis;
  • a Functional Test of Hemiplegic Upper Extremity (FTHUE) score between levels 2 to 6;
  • chronic stroke with onset of neurological condition more than 6 months previously;
  • ability to understand and follow simple verbal instructions;
  • ability to participate in a therapy session lasting at least 30 minutes;
  • community ambulant with or without aids.

排除标准

  • Individuals with severe neglect and severe spasticity (Modified Ashworth Scale >3) would be excluded.

结局指标

主要结局

Fugl-Meyer assessment (FMA)

时间窗: 3-month after the completion of training

FMA-UE is a standard upper limb motor impairment assessment for stroke survivors. FMA-UE assesses voluntary movement, reflex activity, grasp and coordination.

次要结局

  • Action Research Arm Test (ARAT)(3-month after the completion of training)
  • Wolf Motor Function Test (WMFT)(3-month after the completion of training)

研究者

申办方类型
Other
责任方
Sponsor

相似试验