The Effects of Unilateral and Bilateral Mirror Therapy on Upper Extremity Function of Stroke At Acute Stage.
- Conditions
- Stroke, Acute
- Interventions
- Other: unilateral and bilateral mirror therapy
- Registration Number
- NCT06103045
- Lead Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
- Brief Summary
Objective: To comparing the effects of unilateral and bilateral mirror therapy on upper extremity function of stroke at acute stage. We hypothesize there are different effects between unilateral and bilateral mirror therapy on stroke patients at acute stage. Method: Patients with unilateral stroke and the onset within one month will be recruited and then randomly allocated to one of the three groups (including unilateral mirror therapy, bilateral mirror therapy, and conventional occupational therapy). Patient will receive 20 consecutive sessions of intervention (5 time per week, totally 4 weeks) and assessments before and after the intervention within one week. In each intervention session, patients will receive 30 minutes unilateral or bilateral mirror therapy depending on their allocated groups and then 30 conventional occupational therapy. The patients recruited in the conventional occupational therapy group will receive 60 minute conventional therapy. The outcome measures at pre- and post-treatment will including the Fugl-Meyer Assessment for upper extremity (FMA-UE), the Modified Ashworth Scale (MAS), the Jamar Hydraulic Hand Dynamometer, the Chedoke Arm and Hand Activity Inventory (CAHAI), the Revised Nottingham Sensory Assessment (rNSA), and Functional Independence Measurement (FIM).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 30
- Unilateral stroke onset within 1 month
- The score of Mini-Mental State Examination (MMSE) is more than 24
- The score of Fugl-Meyer Assessment for upper extremity (FMA-UE) is between 18 to 56
- The score of Modified Ashworth Scale (MAS) is less than 3
- Willing to receive 3-5 sessions of the intervention per week, total 20 sessions consecutively
- Willing to sign informed consent
- Unstable vital sign or complicating with other symptoms of neurological disease
- Auditory or visual function impairment
- Complicating with perceptual impairment (e.g., apraxia, neglect, or visual agnosia)
- Receiving botulinum toxin injection within 3 months
- Complicating with Wernicke's or Broca's aphasia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Conventional Occupational Therapy (COT) unilateral and bilateral mirror therapy Participants will receive 60 minutes conventional occupational therapy in each treatment session. there will be 20 consecutive sessions (5 times per week, lasting 4 weeks totally) Bilateral Mirror Therapy (BMT) unilateral and bilateral mirror therapy Participants will receive 30 minutes bilateral mirror therapy and then 30 minutes conventional occupational therapy in each treatment session. there will be 20 consecutive sessions (5 times per week, lasting 4 weeks totally) unilateral mirror therapy (UMT) unilateral and bilateral mirror therapy Participants will receive 30 minutes unilateral mirror therapy and then 30 minutes conventional occupational therapy in each treatment session. there will be 20 consecutive sessions (5 times per week, lasting 4 weeks totally)
- Primary Outcome Measures
Name Time Method The Jamar Hydraulic Hand Dynamometer pre-treatment: before intervention within a week; post-treatment: after intervention within a week The Jamar Hydraulic Hand Dynamometer is a gold standard assessment tool for measuring muscle power including the grip strength, palmar pinch, and lateral pinch.
Fugl-Meyer Assessment for upper extremity (FMA-UE) pre-treatment: before intervention within a week; post-treatment: after intervention within a week The FMA-UE is a commonly used assessment in clinical for the extent of motor impairment of upper extremity post-stroke. The score ranged from 0 to 66. The psychometric properties of the FMA-UE had established, and there was also good responsiveness in the past studies.
- Secondary Outcome Measures
Name Time Method Revised Nottingham Sensory Assessment (rNSA) pre-treatment: before intervention within a week; post-treatment: after intervention within a week The rNSA is developed for assessing sensory function of patients with stroke. The reliability of rNSA was established in the past study.
Chedoke Arm and Hand Activity Inventory (CAHAI) pre-treatment: before intervention within a week; post-treatment: after intervention within a week The CAHAI is used for the involvement of the impairment upper extremity during the bimanual tasks. There are 13 item and each score is ranged from 1-7. The psychometric properties of the CAHAI had established in the past studies.
Functional Independence Measurement (FIM) pre-treatment: before intervention within a week; post-treatment: after intervention within a week The FIM was applied for evaluating the independent level and ADL function of the stroke patients. It includes 18 items of self-care, sphincter control, transfers, locomotion, communication, and social cognition. Score of each item is ranged from 1 to 7. The psychometric properties of the FIM had established in the past studies.
Modified Ashworth Scale (MAS) pre-treatment: before intervention within a week; post-treatment: after intervention within a week The MAS is a clinical measurement for muscle spasticity. The score is ranged from 0 to 4. The shoulder, elbow, forearm, wrist, and fingers will be assessed. The psychometric properties of the MAS had established in the past studies.
Trial Locations
- Locations (1)
National Taiwan University Hospital Hsin-Chu Branch
🇨🇳Hsinchu, Taiwan