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Clinical Trials/NCT00796237
NCT00796237
Unknown
N/A

Effects of Whole Body Vibration Training on Bone Health, Physical Fitness, and Neuromotor Performance in Individuals With Subacute Stroke: a Randomized Controlled Trial

The Hong Kong Polytechnic University1 site in 1 country60 target enrollmentMay 2008
ConditionsStroke

Overview

Phase
N/A
Intervention
Not specified
Conditions
Stroke
Sponsor
The Hong Kong Polytechnic University
Enrollment
60
Locations
1
Primary Endpoint
Level of bone resorption marker CTx
Last Updated
14 years ago

Overview

Brief Summary

The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.

Detailed Description

Brief periods of Whole body vibration (WBV) have been shown to improve bone density in post-menopausal women and children with cerebral palsy. In addition to the apparent benefits on bone health, WBV has been shown to increase muscle strength, postural control, muscular blood flow and oxygen uptake in various populations. Therefore, WBV can potentially be used as a tool to improve muscle strength, balance, and cardiovascular performance, especially for those with relatively low level of functioning. Stroke patients are therefore possible beneficiaries of WBV, as they often demonstrate muscle weakness, balance deficits, and poor cardiovascular function, in addition to bone loss. Only one pilot study has examined the effects of WBV in stroke patients. Van Nes et al.showed that postural stability in chronic stroke patients is improved after a few minutes of WBV at 30Hz and 3mm amplitude. The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.

Registry
clinicaltrials.gov
Start Date
May 2008
End Date
December 2011
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • diagnosis of stroke
  • medically stable
  • able to understand simple verbal commands
  • of chinese origin

Exclusion Criteria

  • previous stroke in addition to the current admission
  • other neurological conditions, in addition to stroke
  • significant musculoskeletal or vascular conditions in the lower extremity
  • metal implants in the lower extremity
  • previous fracture in the lower extremity
  • are taking or were taking bone resorption inhibitors

Outcomes

Primary Outcomes

Level of bone resorption marker CTx

Time Frame: baseline, immediately after treatment, and 2-month follow-up

Level of bone formation marker, BSAP

Time Frame: baseline, immediately after treatment, and 2-month follow-up

Secondary Outcomes

  • Six minute walk test(baseline, immediately after treatment, and 2-month follow-up)
  • Ankle arm index(baseline, immediately after treatment, and 2-month follow-up)
  • Functional Ambulation category(baseline, immediately after treatment, and 2-month follow-up)
  • Leg muscle strength (hand-held dynamometry)(baseline, immediately after treatment, and 2-month follow-up)
  • Berg Balance Scale(baseline, immediately after treatment, and 2-month follow-up)
  • Modified Ashworth Scale of Spasticity(baseline, immediately after treatment, and 2-month follow-up)
  • Sensory threshold to light touch in the foot(baseline, immediately after treatment, and 2-month follow-up)
  • Fugl-Meyer Motor Assessment(baseline, immediately after treatment, and 2-month follow-up)

Study Sites (1)

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