Effects of Whole-body Vibration Training on Bone Mass and Bone Metabolism in Adolescents With Down Syndrome / Efectos Del Entrenamiento Vibratorio en la Masa ósea y el Metabolismo óseo de Adolescentes Con síndrome de Down
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Down Syndrome
- Sponsor
- Universidad de Zaragoza
- Enrollment
- 58
- Locations
- 1
- Primary Endpoint
- Changes from baseline in body composition assessed with dual energy X-ray at different time points, 6 months and 15 months.
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The main aims of the present project include 1) to study the longitudinal effects of whole-body vibratory exercise on bone metabolism in adolescents with and without DS and 2) to evaluate whether a low frequency vibratory training program consisting of 3 sessions per week for 9 months (each vibratory session last approximately 10 minutes and includes 5-6 bouts of 1 min with 1 min rest between bouts) can improve bone development in these populations. Finally, and additional aim of the project is 3) to determine how long these effects may last after the end of the intervention.
Investigators
José A. Casajús
MD, PhD.
Universidad de Zaragoza
Eligibility Criteria
Inclusion Criteria
- •Both groups: Ages 10 -
- •Both groups: Parental/guardian permission (informed consent) and if appropriate, child verbal assent.
- •Down syndrome group only: Diagnosis of Down syndrome.
Exclusion Criteria
- •Taking medication affecting bone.
- •Non-caucasian.
Outcomes
Primary Outcomes
Changes from baseline in body composition assessed with dual energy X-ray at different time points, 6 months and 15 months.
Time Frame: Changes from baseline in body composition at 6 months and changes from baseline in body composition at 15 months
Secondary Outcomes
- Changes from baseline in bone structure evaluated with peripheral quantitative computed tomography at different time points, 6 months and 15 months.(Changes from baseline in bone structure at 6 months and changes from baseline in bone structure at 15 months)