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Clinical Trials/CTRI/2021/06/034242
CTRI/2021/06/034242
Recruiting
未知

Clinical, electrophysiological spectrum and predictors of dysautonomia and successful extubation in Guillian Barre syndrome: a prospective cohort study.

I0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
I
Status
Recruiting
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Observational

Investigators

Sponsor
I

Eligibility Criteria

Inclusion Criteria

  • Patients with GBS, based on clinical, CSF and electro\-diagnostic criteria will be included in this study.
  • GBS patients with clinical evidence (defined below) of sympathetic hyperactivity will receive prazosin and titrated as per patientâ??s requirement.
  • clinical evidence of sympathetic hyperactivity includes cold and clammy skin (after ruling out dehydration), presence of hypertension (SBP \> 140/90 mmHg) for more than 2 hours with or without pulmonary edema or Labile BP (defined as BP differences of \>40mmHg in a single day) or Resting Tachycardia ( \> 125 beats per minute) for 2 hours.

Exclusion Criteria

  • Patients with hypo or hyperkalemic paralysis, toxins, porphyria, viral myositis, MND, Cervical myelopathy and CSF cell \> 50/mm3 will be excluded.
  • GBS patients with Hypotension (systolic blood pressure \< 90 mmHg) and bradycardia ( \< 48 beats per minute) will also be excluded.

Outcomes

Primary Outcomes

Not specified

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