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临床试验/CTRI/2021/06/034242
CTRI/2021/06/034242招募中未知

Clinical, electrophysiological spectrum and predictors of dysautonomia and successful extubation in Guillian Barre syndrome: a prospective cohort study.

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试验速览

阶段
未知
状态
招募中
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

入选标准

  • Patients with GBS, based on clinical, CSF and electro-diagnostic criteria will be included in this study.
  • GBS patients with clinical evidence (defined below) of sympathetic hyperactivity will receive prazosin and titrated as per patientâ??s requirement.
  • clinical evidence of sympathetic hyperactivity includes cold and clammy skin (after ruling out dehydration), presence of hypertension (SBP > 140/90 mmHg) for more than 2 hours with or without pulmonary edema or Labile BP (defined as BP differences of >40mmHg in a single day) or Resting Tachycardia ( > 125 beats per minute) for 2 hours.

排除标准

  • Patients with hypo or hyperkalemic paralysis, toxins, porphyria, viral myositis, MND, Cervical myelopathy and CSF cell > 50/mm3 will be excluded.
  • GBS patients with Hypotension (systolic blood pressure < 90 mmHg) and bradycardia ( < 48 beats per minute) will also be excluded.

研究者

发起方
I

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