CTRI/2021/06/034242
Recruiting
未知
Clinical, electrophysiological spectrum and predictors of dysautonomia and successful extubation in Guillian Barre syndrome: a prospective cohort study.
I0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- I
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with GBS, based on clinical, CSF and electro\-diagnostic criteria will be included in this study.
- •GBS patients with clinical evidence (defined below) of sympathetic hyperactivity will receive prazosin and titrated as per patientâ??s requirement.
- •clinical evidence of sympathetic hyperactivity includes cold and clammy skin (after ruling out dehydration), presence of hypertension (SBP \> 140/90 mmHg) for more than 2 hours with or without pulmonary edema or Labile BP (defined as BP differences of \>40mmHg in a single day) or Resting Tachycardia ( \> 125 beats per minute) for 2 hours.
Exclusion Criteria
- •Patients with hypo or hyperkalemic paralysis, toxins, porphyria, viral myositis, MND, Cervical myelopathy and CSF cell \> 50/mm3 will be excluded.
- •GBS patients with Hypotension (systolic blood pressure \< 90 mmHg) and bradycardia ( \< 48 beats per minute) will also be excluded.
Outcomes
Primary Outcomes
Not specified
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