The Treatment of Late Life Major Depression Complication by Alcohol

US Department of Veterans Affairs1 site in 1 country74 target enrollmentOctober 1999

ConditionsAlcoholism Depression

InterventionsNALTREXONE Placebo

DrugsNALTREXONE Placebo

Overview

Phase: Phase 4
Intervention: NALTREXONE
Conditions: Alcoholism
Sponsor: US Department of Veterans Affairs
Enrollment: 74
Locations: 1
Primary Endpoint: Alcohol use'
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to test the efficacy combining a treatment for depression with a treatment for alcohol dependence.

Detailed Description

This study aims to study 80 patients with comorbid alcohol dependence and a depressive syndrome. After appropriate detoxification, patients are started on either naltrexone 50 mg or placebo. After one week, sertraline is added in an open label fashion. It is hypothesized that those patients receiving combination therapy will last 3 months with follow-up tracking lasting 1 year.

Registry

clinicaltrials.gov

Start Date

October 1999

End Date

January 2005

Last Updated

16 years ago

Study Type

Interventional

Study Design

Single Group