NCT00018824已完成4 期
The Treatment of Late Life Major Depression Complication by Alcohol
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Alcohol use'
研究概览
简要总结
The purpose of this study is to test the efficacy combining a treatment for depression with a treatment for alcohol dependence.
详细描述
This study aims to study 80 patients with comorbid alcohol dependence and a depressive syndrome. After appropriate detoxification, patients are started on either naltrexone 50 mg or placebo. After one week, sertraline is added in an open label fashion. It is hypothesized that those patients receiving combination therapy will last 3 months with follow-up tracking lasting 1 year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 55
- •Current depressive syndrome
- •Current alcohol dependence
- •No psychosis
- •No opioid or cocaine abuse or dependence
排除标准
- 未提供
研究组 & 干预措施
1
Experimental
Naltrexone
干预措施: NALTREXONE (Drug)
2
Placebo Comparator
Placebo
干预措施: Placebo (Drug)
结局指标
主要结局
Alcohol use'
时间窗: 12 weeks
次要结局
未报告次要终点
研究者
研究点 (1)
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