“Clinical and epidemiologic study of potentially malignant lesions and conditions of oral cavity in rural areas of Sangli districtâ€
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 入组人数
- 2,500
- 试验地点
- 1
- 主要终点
- Incidence and prevalence of oral precancer lesions and conditions
研究概览
简要总结
Oral cancer has become a global health problem and its increasing incidence and mortality rates are particularly relavant in certain parts of India.
Worldwide, oral cancer has one of the lowest survival rates that remain unalterd despite recent therapeutic advances. Early detection is widely recognized as the corner stone to reduce diagnostic delay and thus to improve survival. In many instances a significant proportion of oral squamous cell carcinomas developed from premalignant lesions and conditions such as leukoplakia, submucous fibrosis and lichen planus.
Identification of this oral premalignant lesions is very important in order to prevent malignant transformation and its related morbodity and mortality. The demographic details, sites and type of lesions, habits and its frequency of consumption, duration and type of habits including smoking and non smoking form, mixed habits and alcohol consumption can be studied in this respect and these hold much promice in creating awareness about association of these habits with oral precancer and cancer. Western Maharashtra is one of the important hub for tobacco manufacturing and studies have reported increased incidence of oral cancer in association with tobacco usage. Not many epidemiological studies have been conducted regarding oral precancer and hence our project aims to study the same in the rural areas of Sangli district and to creat awareness amongst the population about the deleterious effects of consumption of tobacco, areca nut and alcohol.
This cross sectional study will be carried out in the rural areas of Sangli district. Informed written consent will be obtained prior to beginning of the study. Demographic details, socioeconomic status, information related to consumption of tobacco, areca nut and alcohol or other habits will be recorded. Oral examination of all the patients will be conducted day light with help of the diagnostic instruments. Patient awareness education will be given regarding the habits and its deleterious effects. All records entered will be cross- checked for correctness. The entire data obtained will be entered in MS Excel and analyzed in statistical package for social sciences (SPSS)
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects with habit of chewing tobacco or areca nut, smoking tobacco, or alcohol consumption or any other habit 2) having signs of Oral premalignant lesions and conditions like leukoplakia, erythroplakia, oral submucus fibrosis and lichen planus.
排除标准
- •Patients with white or red lesions other than oral premalignant lesions and conditions Patients with oral cancer Subjects not willing to participate in the study.
结局指标
主要结局
Incidence and prevalence of oral precancer lesions and conditions
时间窗: Period of 4 months
次要结局
- epidemiological study of oral precancer in western maharashtra(2 years)
