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Nanobiotix

🇫🇷France
Ownership
-
Employees
102
Market Cap
-
Website
Introduction

Nanobiotix SA is a late-stage biotechnology company, which engages in the development of therapeutic approaches to the treatment of cancer. Its technologies include NanoXray that improves the efficacy of radiation therapy against tumor cells. The company was founded by Laurent Lévy and Abdel Kader Boussaha on March 4, 2003 and is headquartered in Paris, France.

Clinical Trials

8

Active:1
Completed:2

Trial Phases

4 Phases

Phase 1:4
Phase 2:1
Phase 3:1
+1 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (7 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (57.1%)
Not Applicable
1 (14.3%)
Phase 2
1 (14.3%)
Phase 3
1 (14.3%)

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Phase 3
Recruiting
Conditions
Locally Advanced Head and Neck Squamous Cell Carcinoma
Aged
Interventions
Drug: JNJ-90301900 (NBTXR3)
Radiation: Radiation Therapy
First Posted Date
2021-05-19
Last Posted Date
2025-08-17
Lead Sponsor
Johnson & Johnson Enterprise Innovation Inc.
Target Recruit Count
500
Registration Number
NCT04892173
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Memorial Radiation Oncology Medical Group Laguna Hills, Laguna Hills, California, United States

🇺🇸

UCLA Hematology Oncology, Los Angeles, California, United States

and more 166 locations

NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD-1 Therapy

Phase 1
Recruiting
Conditions
Radiotherapy
Immunotherapy
Microsatellite Instability-High Solid Malignant Tumour
Metastasis from Malignant Tumor of Liver
Squamous Cell Carcinoma of Head and Neck
Metastasis from Malignant Tumor of Cervix
Metastasis from Malignant Melanoma of Skin (disorder)
Metastatic Triple-Negative Breast Carcinoma
Metastatic NSCLC
Metastatic Renal Cell Carcinoma
Interventions
First Posted Date
2018-07-17
Last Posted Date
2025-01-14
Lead Sponsor
Nanobiotix
Target Recruit Count
145
Registration Number
NCT03589339
Locations
🇺🇸

University of California San Francisco, San Francisco, California, United States

🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

🇺🇸

Emory University, Atlanta, Georgia, United States

and more 10 locations

NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate Adenocarcinoma

Phase 1
Terminated
Conditions
Prostate Cancer
Interventions
Drug: NBTXR3 activated by IMRT only
Drug: NBTXR3 activated by Brachytherapy & IMRT
First Posted Date
2016-06-20
Last Posted Date
2021-05-10
Lead Sponsor
Nanobiotix
Target Recruit Count
5
Registration Number
NCT02805894
Locations
🇺🇸

Dana Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts, United States

🇺🇸

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

NBTXR3 Crystalline Nanoparticles and Stereotactic Body Radiation Therapy in the Treatment of Liver Cancers

Phase 1
Terminated
Conditions
Liver Cancer
First Posted Date
2016-03-28
Last Posted Date
2021-05-10
Lead Sponsor
Nanobiotix
Target Recruit Count
23
Registration Number
NCT02721056
Locations
🇫🇷

CHU La Croix Rousse, Lyon, France

🇫🇷

Institut de Cancérologie de Loraine, Nancy, France

🇫🇷

CHU de NANCY, Nancy, France

and more 4 locations

NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall

Phase 2
Completed
Conditions
Adult Soft Tissue Sarcoma
First Posted Date
2015-03-05
Last Posted Date
2021-04-06
Lead Sponsor
Nanobiotix
Target Recruit Count
180
Registration Number
NCT02379845
Locations
🇦🇺

Capital Region Cancer Service, Canberra Hospital, Canberra, Australia

🇦🇺

Chris O'Brien Lifehouse, Sydney, Australia

🇧🇪

Jules Bordet Institute, Bruxelles, Belgium

and more 39 locations
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News

Nanobiotix Secures EU Regulatory Harmonization and New Patent for Cancer Radioenhancer JNJ-1900

European health authorities have reclassified JNJ-1900 (NBTXR3) from a medical device to a medicinal product, harmonizing its regulatory status with the US and other major markets.

JNJ-1900 Shows Promise in Phase 1 Trial for Advanced Pancreatic Cancer

JNJ-1900 (NBTXR3) demonstrated favorable safety and feasibility in a Phase 1 trial involving 22 patients with locally advanced or borderline resectable pancreatic cancer.

Nanobiotix's Radioenhancer JNJ-1900 Enters Phase 2 Trial for Unresectable NSCLC

Nanobiotix has dosed the first patient in the CONVERGE study, a Phase 2 trial evaluating JNJ-1900 (NBTXR3) for Stage 3 unresectable non-small cell lung cancer.

Nanobiotix Transfers US Sponsorship of NANORAY-312 to Janssen, Anticipates Key Data Readouts

Nanobiotix transferred the US sponsorship of the Phase 3 NANORAY-312 head and neck cancer study to Janssen, a key step for NBTXR3 regulatory submission.

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