MedPath

Nanobiotix

🇫🇷France
Ownership
-
Employees
102
Market Cap
-
Website
Introduction

Nanobiotix SA is a late-stage biotechnology company, which engages in the development of therapeutic approaches to the treatment of cancer. Its technologies include NanoXray that improves the efficacy of radiation therapy against tumor cells. The company was founded by Laurent Lévy and Abdel Kader Boussaha on March 4, 2003 and is headquartered in Paris, France.

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Phase 3
Recruiting
Conditions
Locally Advanced Head and Neck Squamous Cell Carcinoma
Aged
Interventions
Drug: JNJ-90301900 (NBTXR3)
Radiation: Radiation Therapy
First Posted Date
2021-05-19
Last Posted Date
2025-04-03
Lead Sponsor
Johnson & Johnson Enterprise Innovation Inc.
Target Recruit Count
500
Registration Number
NCT04892173
Locations
🇮🇳

Apollo Speciality Hospital, Chennai, Chennai, India

🇮🇳

Meenakshi Mission Hospital and Research Center, Madhurai, India

🇪🇸

Hosp. Gral. Univ. Valencia, Valencia, Spain

and more 156 locations

NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD-1 Therapy

Phase 1
Recruiting
Conditions
Radiotherapy
Immunotherapy
Microsatellite Instability-High Solid Malignant Tumour
Metastasis from Malignant Tumor of Liver
Squamous Cell Carcinoma of Head and Neck
Metastasis from Malignant Tumor of Cervix
Metastasis from Malignant Melanoma of Skin (disorder)
Metastatic Triple-Negative Breast Carcinoma
Metastatic NSCLC
Metastatic Renal Cell Carcinoma
Interventions
First Posted Date
2018-07-17
Last Posted Date
2025-01-14
Lead Sponsor
Nanobiotix
Target Recruit Count
145
Registration Number
NCT03589339
Locations
🇺🇸

Christus St. Vincent Regional Cancer Center, Santa Fe, New Mexico, United States

🇺🇸

St Luke's University Health Network, Bethlehem, Pennsylvania, United States

🇺🇸

Sanford Cancer Center, Sioux Falls, South Dakota, United States

and more 10 locations

NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate Adenocarcinoma

Phase 1
Terminated
Conditions
Prostate Cancer
Interventions
Drug: NBTXR3 activated by IMRT only
Drug: NBTXR3 activated by Brachytherapy & IMRT
First Posted Date
2016-06-20
Last Posted Date
2021-05-10
Lead Sponsor
Nanobiotix
Target Recruit Count
5
Registration Number
NCT02805894
Locations
🇺🇸

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

🇺🇸

Dana Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts, United States

NBTXR3 Crystalline Nanoparticles and Stereotactic Body Radiation Therapy in the Treatment of Liver Cancers

Phase 1
Terminated
Conditions
Liver Cancer
Interventions
Radiation: NBTXR3, IL or IA injection + SBRT
First Posted Date
2016-03-28
Last Posted Date
2021-05-10
Lead Sponsor
Nanobiotix
Target Recruit Count
23
Registration Number
NCT02721056
Locations
🇫🇷

Centre René Gauducheau, Nantes, France

🇫🇷

Institut de Cancérologie de Loraine, Nancy, France

🇫🇷

Hôpital Haut-Lévêque, Pessac, France

and more 4 locations

NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall

Phase 2
Completed
Conditions
Adult Soft Tissue Sarcoma
Interventions
Device: Radiation therapy
Device: NBTXR3
First Posted Date
2015-03-05
Last Posted Date
2021-04-06
Lead Sponsor
Nanobiotix
Target Recruit Count
180
Registration Number
NCT02379845
Locations
🇦🇺

Chris O'Brien Lifehouse, Sydney, Australia

🇦🇺

Capital Region Cancer Service, Canberra Hospital, Canberra, Australia

🇧🇪

Jules Bordet Institute, Bruxelles, Belgium

and more 39 locations

NBTXR3 and Radiation Therapy in Treating Patients With Locally Advanced SCC of the Oral Cavity or Oropharynx

Not Applicable
Active, not recruiting
Conditions
Head and Neck Cancer
Interventions
Device: NBTXR3 activated by IMRT
First Posted Date
2013-09-20
Last Posted Date
2022-12-29
Lead Sponsor
Nanobiotix
Target Recruit Count
75
Registration Number
NCT01946867
Locations
🇭🇺

Hungarian Defense Forces Hospital, Budapest, Hungary

🇪🇸

Hospital Fundación Jimenez Diaz, Madrid, Spain

🇵🇱

Centrum Onkologii - Instytut im. M. Skłodowskiej- Curie, Oddział w Gliwicach, Gliwice, Poland

and more 17 locations

NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma of the Extremity

Phase 1
Completed
Conditions
Adult Soft Tissue Sarcoma
Interventions
Device: NBTXR3
First Posted Date
2011-09-13
Last Posted Date
2020-10-06
Lead Sponsor
Nanobiotix
Target Recruit Count
22
Registration Number
NCT01433068
Locations
🇫🇷

Institut Bergonie, Bordeaux, France

🇫🇷

Institut Gustave Roussy, Villejuif, France

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