NL-OMON40010已完成不适用
Effects and Cost-Effectiveness of Pharmacogenetic Screening among Elderly Starters with Antidepressants: A Pragmatic Randomized Controlled Trial - Cytochrome P450-2D6 screening in elderly using antidepressants
Rijksuniversiteit Groningen0 个研究点目标入组 750 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 750
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •*Age 60 years or older
- •*Major depression according to DSM-IV criteria for which the treating psychiatrist decided to start drug treatment with either nortriptyline or venlafaxine
- •*Competent to understand the informed consent procedure
排除标准
- •*Use of clinically relevant CYP2D6 inhibitors (e.g. fluoxetine, paroxetine, quinidine, ritonavir, efavirenz)
- •*Use of clinically relevant CYP2D6 inducers (e.g. dexamethasone, rifampicine)
- •*Use of other drugs that affect plasma levels as co-medication
- •*Serious hepatic failure (ASAT/ALAT or gamma-GT * twice the maximal reference value)
- •*Patients for which drug treatment with venlafaxine is started and a GFR < 30 ml/min.
- •*Patienst with the very rare genotype: Intermediate Metabolizer with duplications (IMDUP).
研究者
相似试验
已完成
不适用
Pharmacoeconomic analysis of warfarin therapyCTRI/2017/08/009274King Edward Memorial Hospital280
已完成
Unknown
Clinical and Humanistic Outcomes of Pharmaceutical Care Interventions for Type 2 Diabetes Patients: A Randomized Controlled Trial.Circulatory SystemNutritional, Metabolic, EndocrineCardiologyPACTR202311849462910Federal Medical Centre Abakaliki20
进行中（未招募）
1 期
Pharmacogenetic Study of CellCept (Mycophenolate Mofetil) in Kidney Transplant PatientsRenal TransplantationMedDRA version: 19.0Level: LLTClassification code 10023438Term: Kidney transplantSystem Organ Class: 100000004865EUCTR2016-001042-25-Outside-EU/EEAF. Hoffmann-La Roche AG720
已完成
Unknown
Outcomes of Pharmaceutical Care Interventions in Type 2 Diabetes Mellitus Patients: A Pre-Post Pilot Study At Federal Medical Center Abakaliki, Ebonyi State, Nigeria.Kidney DiseasePACTR202311731445746Pharm. Solomon Ikechukwu Okorie16
尚未招募
4 期
Effect and costs of methods to avoid tooth decay in poor 6 - 7 year old children in Bengaluru city - an experiment done in the school premisesCTRI/2015/06/005946The Oxford Dental College440