Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit
- Conditions
- Blood Lactate Analysis
- Interventions
- Procedure: Blood Lactate Analysis
- Registration Number
- NCT01624519
- Lead Sponsor
- University of California, Los Angeles
- Brief Summary
The main objective of this study is to examine the agreement between arterial, central venous, and peripheral venous lactate values in a population of medical Intensive Care Unit (ICU) patients.
- Detailed Description
This study is a single-center, prospective trial to assess the agreement between arterial, central venous, and peripheral venous lactate measurements. When an arterial lactate is deemed to be necessary as part of ICU management, a central venous and peripheral venous sample will also obtained within 5 minutes. All of the samples will be analyzed using the same analyzer as quickly as possible. A maximum of 10 paired arterial and venous lactate samples will be obtained per patient to prevent a single patient from dominating the data set. Additional data collected on a standardized data collection form will include primary diagnosis, intubation status, use of inotropic agents, hypotension (defined as a systolic blood pressure \< 90 mm Hg), ICU length of stay and mortality. The Bland-Altman method will be used to assess agreement between arterial (A), central venous(CV), and peripheral venous (PV) lactate measurements. Approximately 50 patients will be enrolled in this study.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
- Adult patients 18 years or older
- Admitted to the Intensive Care Unit (ICU)
- Determined by their treating clinicians to require both a central venous line and arterial line
- None
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 Blood Lactate Analysis -
- Primary Outcome Measures
Name Time Method Agreement between peripheral venous, central venous, and arterial lactate values in a population of medical Intensive Care Unit (ICU) patients. 1 year
- Secondary Outcome Measures
Name Time Method