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Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit

Not Applicable
Conditions
Blood Lactate Analysis
Interventions
Procedure: Blood Lactate Analysis
Registration Number
NCT01624519
Lead Sponsor
University of California, Los Angeles
Brief Summary

The main objective of this study is to examine the agreement between arterial, central venous, and peripheral venous lactate values in a population of medical Intensive Care Unit (ICU) patients.

Detailed Description

This study is a single-center, prospective trial to assess the agreement between arterial, central venous, and peripheral venous lactate measurements. When an arterial lactate is deemed to be necessary as part of ICU management, a central venous and peripheral venous sample will also obtained within 5 minutes. All of the samples will be analyzed using the same analyzer as quickly as possible. A maximum of 10 paired arterial and venous lactate samples will be obtained per patient to prevent a single patient from dominating the data set. Additional data collected on a standardized data collection form will include primary diagnosis, intubation status, use of inotropic agents, hypotension (defined as a systolic blood pressure \< 90 mm Hg), ICU length of stay and mortality. The Bland-Altman method will be used to assess agreement between arterial (A), central venous(CV), and peripheral venous (PV) lactate measurements. Approximately 50 patients will be enrolled in this study.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Adult patients 18 years or older
  • Admitted to the Intensive Care Unit (ICU)
  • Determined by their treating clinicians to require both a central venous line and arterial line
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Exclusion Criteria
  • None
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
1Blood Lactate Analysis-
Primary Outcome Measures
NameTimeMethod
Agreement between peripheral venous, central venous, and arterial lactate values in a population of medical Intensive Care Unit (ICU) patients.1 year
Secondary Outcome Measures
NameTimeMethod
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