Genetic risk factors for oral cavity cancer.
Not Applicable
- Conditions
- Health Condition 1: C060- Malignant neoplasm of cheek mucosa
- Registration Number
- CTRI/2018/10/016079
- Lead Sponsor
- ational Cancer Grid
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. All new histopathologically confirmed primary buccal mucosa cancer cases
1.1. Buccal Mucosa Cancer cases definition (ICD-O-3):-
• Cheek mucosa (C06.0)
• Retromolar areas (C06.2)
• Buccoalveolar sulci, upper and lower (vestibule of mouth) (C06.1)
2. Date of diagnosis less than 6 months from the date of enrolment
3. Age between 20-65 years
4. Resident of India for at least one year
Exclusion Criteria
1. Pregnant women.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Conduct a large-scale multicentre genome-wide association (GWA) study to investigate the role <br/ ><br>of genetic susceptibility in Buccal Mucosa Cancer. <br/ ><br>2. To study the interaction of genetic susceptibility with lifestyle factors. <br/ ><br>3. To explore the role of smoking behavior and/or tobacco chewing and nicotine dependent genetic <br/ ><br>loci in Indian origin population.Timepoint: 2 years
- Secondary Outcome Measures
Name Time Method nilTimepoint: nil