Quantitative Assessment of Myocardial Perfusion with Magnetic Resonance Using an Intravascular Contrast Agent

King's College London0 个研究点开始时间: 2008年10月31日最近更新: 2012年3月19日

适应症

试验速览

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•Patients referred for MR adenosine stress perfusion, with or without known coronary artery disease, with or without prior myocardial revascularization
•The subject is =18 years of age
•The subject is conscious and able to comply with the study procedures
•Written informed consent has been obtained
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Contraindications for MRI
•Contraindications to Gadolinium based contrast agents (known allergies or a contra indication to Gd
•chelates or renal insufficiency)
•Contraindications to Adenosine stress
•Myocardial infarction <3 days
•Unstable angina pectoris
•Severe arterial hypertension
•Asthma or severe obstructive pulmonary disease requiring treatment (chronic obstructive pulmonary disease COPD)
•Sick sinus syndrome or a symptomatic bradycardia, AV block >IIa, trifascicular block
•Allergy against vasodilator
•Allergy against Gadolinium based contrast agents or renal insufficiency
•Other contraindications for adenosine or dipyridamole administration
•Heart failure (NYHA IV)
•The subject’s ECG shows prolonged QT interval
•Severe arterial hypotension (< 90 mmHg systolic)
•Claustrophobia

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