Role of Baclofen and topiramate in alcoholism
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Alcohol Dependence Syndrome
- Registration Number
- CTRI/2016/01/006525
- Lead Sponsor
- Government Medical College Hospital GMCH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
a)age 18-65 years
b) males
c) patients meeting diagnostic criteria for alcohol dependence as per ICD-10 classification
Exclusion Criteria
a) Presence of serious physical illness such as renal dysfunction, seizure disorder, cardiac disease (as assessed by thorough physical examination ,past history and routine laboratory screening) b) Presence of another current co-existing major psychiatric disorder c) Presence of another current drug abuse except nicotine and caffeine d) Patients with history of hypersensitivity reaction with these drugs in past e) Patient not willing to consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Craving by Obsessive and Compulsive Drinking Scale (OCDS), Motivation by Readiness to Change Questionnaire, withdrawal symptoms by CIWA-Ar, Side effects of drugs using checklistTimepoint: At Week 1,2,3,4,6,8,10 and 12
- Secondary Outcome Measures
Name Time Method Craving by Obsessive and Compulsive Drinking Scale (OCDS) and Visual Analogue scale (VAS),Quality of life by WHO QOL-Bref, Field Trial Version(Hindi version),Hemogram, SERFT, LFT, side effects checklistTimepoint: baseline,week 4,8,12