Predictive Factors of Disease-free Survival After Complete Pathological Response to Neoadjuvant Radiotherapy in Rectal Adenocarcinoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 8
- 主要终点
- Distant recurrence rate
研究概览
简要总结
Many data suggest that patients with low rectal adenocarcinoma who achieved ypT0N0 status have improved survival and disease-free survival (DFS) compared to all other stages however only few data are available regarding the specific prognosis factors of this subgroup. This retrospective multicentric study aimed to predict the prognosis of patients with complete pathological response after neoadjuvant treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •all patients with metastatic tumors or missing data
结局指标
主要结局
Distant recurrence rate
时间窗: From date of surgery until the date of first documented distant progression assessed up to 100 months
A postoperative distant recurrence was defined by biopsy-proven or radiographic evidence of distant recurrent disease.
Local recurrence rate
时间窗: From date of surgery until the date of first documented local progression assessed up to 100 months
A postoperative local recurrence was defined by biopsy-proven or radiographic evidence of local recurrent disease.
次要结局
- Predictive factors of disease free survival(From date of surgery until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 100 months)