VTE Incidence After Curative Colon Cancer Surgery in an ERAS Program

Completed

Brief Summary: Based on data on a cohort of 2,141 patients undergoing elective colonic cancer resection in an ERAS program, the incidence of postoperative thromboembolic events is estimated in patients no receiving prolonged thromboembolic prophylaxis.

Detailed Description: The Copenhagen cOmplete Mesocolic Excision Study (COMES) database contains comprehensive data on preoperative, intraoperative, postoperative and tumor related variable on patients undergoing elective colonic cancer resection at four public university clinics providing all colorectal cancer treatment for the 1.8 million residents of the Capital Region of Denmark during the period 2014-2017.

None of these hospitals had implemented prolonged thromboembolic prophylaxis after discharge.

The medical records were reviewed with focusing on VTE prophylaxis, ongoing preoperative and postoperative anticoagulant treatment, the length of hospital stay (LOS), and readmission to ensure high data validity.

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

concomitant rectum resection
soly appendix carcinoma
diagnosed with pulmonary embolism or deep venous thrombosis before primary discharge
dying before discharge from the hospital or discharged at postoperative day 28 or later
treatment with vitamin K antagonists, heparin or new oral anticoagulants before or after surgery
VTE less than 3 months before the colon resection

Primary Outcome Measures

Name	Time	Method
Postoperative venous thromboembolic event	60 days	Deep venous thrombosis or pulmonary embolism

Secondary Outcome Measures

Name	Time	Method

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