A Study Investigating Properties of the Transversus Abdominis Plane Block

Not Applicable

Completed

• Conditions: Anesthesia, Local
• Interventions: Drug: Ropivacaine

• Registration Number: NCT01679392
• Lead Sponsor: Hillerod Hospital, Denmark

Brief Summary

In this study we investigate the following properties of the transversus abdominis plane block in healthy volunteers:

1. Cutaneous analgesic distribution

2. Muscular affection

3. Reproducibility

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08
• Study First Submitted: 2012-08-27
• Study First Submitted QC: 2012-09-05
• Study First Posted: 2012-09-06
• Primary Completion: 2013-03
• Study Completion: 2013-05
• Status Verified: 2015-03
• Last Update Submitted: 2015-03-19
• Last Update Posted: 2015-03-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Capable
• American society of anesthesiologists classification 1 or 2
• Written informed consent

Exclusion Criteria

• Age below 18 years
• American society of anesthesiologists classification above 2
• Body weight below 50 kg
• Body mass index > 35 kg/m2
• Previous abdominal surgery
• Acute or chronic pain
• Use of pain medication less than 24 h prior to study start
• Allergy to local anesthetics
• Pregnancy
• Breastfeeding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Ropivacaine	Ropivacaine	Unilateral transversus abdominis plane block with 20 ml ropivacaine (7.5 mg/ml)

Primary Outcome Measures

Name	Time	Method
Cutaneous analgesic distribution	90 min	Cutaneous analgesic distribution 90 min after transversus abdominis plane block administration

Secondary Outcome Measures

Name	Time	Method
Muscular affection of the transversus abdominis plane block	90 min	Abdominal wall muscle affection of the transversus abdominal plane block measured by ultrasonography under standardized conditions
Reproducibility of the transversus abdominis plane block	At least 2 days	Reproducibility of the transversus abdominis plane block with respect to: 1. Cutaneous analgesic distribution; 2. Abdominal wall muscle affection measured in the same individual separated by at least 2 days

Trial Locations

Locations (1)

Hillerød Hospital; 🇩🇰 Hillerød, Denmark