Non-invasive Ventilation Prevents Post-operative Respiratory Failure in Patient Undergoing Bariatric Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- University of Campania "Luigi Vanvitelli"
- Enrollment
- 107
- Locations
- 1
- Primary Endpoint
- Intensive care unit admission rate
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Postoperative non-invasive ventilation (NIV) has been proposed as an attractive strategy to reduce morbidity and improve postoperative outcomes in obese subjects undergoing general anesthesia. Bariatric patients present a peculiar negative feature; the increased body mass index (BMI) correlates with loss of perioperative functional residual capacity (FRC), expiratory reserve volume (ERV) and total lung capacity (TLC), decreased up to 50% of preoperative values. The aim of the current randomized trial is to evaluate the efficacy of NIV in post-anaesthesia care unit (PACU) in reducing post-extubation acute respiratory failure and the consequent admission in intensive care units (ICU) after BIBP in obese adult patients.
Investigators
Claudio Gambardella
Clinical Professor
University of Campania "Luigi Vanvitelli"
Eligibility Criteria
Inclusion Criteria
- •Morbid Obesity
- •Patients undergoing Biliointestinal Bypass (BIBP)
Exclusion Criteria
- •Patients requiring emergency operation with rapid sequence induction
- •Patients with suspected presence of difficult airway or pre-existing lung impairment
- •Pregnancy
- •Severe renal dysfunction,
- •cardiac disease resulting in marked limitation of physical activity, corresponding to NYHA class \>II
Outcomes
Primary Outcomes
Intensive care unit admission rate
Time Frame: 72 hours
The primary outcome was the evaluation of the ICU admission rate after NIV in postoperative management of obese patients
Blood oxygen saturation (SaPo2)
Time Frame: 12 hours
the evaluation of the oximetry values of obese patients after postoperative NIV adoption