Clinical Characteristics, Management Patterns and Outcomes of Type A Aortic Dissection: A Sino-US Comparative Cohort Analysis

Completed

• Conditions: Aortic Dissection
• Interventions: Procedure: surgery

• Registration Number: NCT05409469
• Lead Sponsor: Xin Chen

Brief Summary

This study constructed a retrospective cohort study by retrospectively analyzing the data of all patients with aortic dissection from January 1, 2012 to December 31, 2021 from the Cardiovascular Disease Registration System of Jiangsu Province in China and the data of similar diseases in recent years from National Inpatient Sample database in the United States

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01
• Primary Completion: 2021-12
• Study Completion: 2021-12
• Status Verified: 2022-05
• Study First Submitted: 2022-05-20
• Study First Submitted QC: 2022-06-05
• Last Update Submitted: 2022-06-05
• Study First Posted: 2022-06-08
• Last Update Posted: 2022-06-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11550

Inclusion Criteria

1.Clinical diagnosis of type A Aortic Dissection

Exclusion Criteria

1. age<18, age unknown,
2. diagnosis of aortic aneurysm, transfer out within 1 day,
3. unknown vital status at discharge;
4. unknown treatment type: cardioplegia, valve or cardiac repair only without aortic repair or two types of treatments on different days

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Chinese patients with aortic dissection	surgery	Clinical characteristics, management patterns and outcomes of type A aortic dissection in China.
American patients with aortic dissection	surgery	Clinical characteristics, management patterns and outcomes of type A aortic dissection in the United States.

Primary Outcome Measures

Name	Time	Method
Baseline data of patients with type A aortic dissection was assessed by SPSS 17.0	from 2015 to 2019	Baseline data of patients with type A aortic dissection included gender, age,height, weight, past medical history, family history, hospital costs, etc.
The main efficacy indicators was assessed by SPSS 17.0.	from 2015 to 2019	The main efficacy indicators included surgical procedures, surgical outcome (postoperative bleeding, ICU stay, extubation time), perioperative complications (including infection, bleeding, neurological complications, cardic complications, renal insufficiency, etc.), and postoperative mortality.