A comparative study between recepient site preparation using dermabrasion, liquid nitrogen induced blister and dermarolling system in autologous non cultured epidermal cell suspension procedure in stable vitiligo patients

Not Applicable

Completed

• Conditions: Health Condition 1: L80- Vitiligo

• Registration Number: CTRI/2018/12/016735
• Lead Sponsor: Post graduate institute of medical education and research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-12-27
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 36

Inclusion Criteria

1. Patients with a clinical diagnosis of generalized vitiligo

2. Patients with symmetrical lesions of size > 1.5cm x 1cm present on trunk or extremities including acral areas.

3. Vitiligo lesions has been stable for 1 year.

4. Disease not responding to medical treatment, or there are residual patches (after medical therapy) of vitiligo .

5. Maximum size of vitiligo patches to be selected for surgery will not be >100cm2.

Exclusion Criteria

Age less than 18 years

2) Pregnancy and lactation

3) Patient with actively spreading vitiligo

4) History of Koebnerisation

5) History of hypertrophic scars or keloidal tendency

6) Bleeding disorders

7) Patients with unrealistic expectation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the difference in extent of repigmentation by the three different methods at 12 weeks of post treatment follow up in a given patient of stable vitiligo. Repigmentation will be assessed as follows: <br/ ><br>â?¤25% Minimal repigmentation <br/ ><br>26-50% Mild repigmentation <br/ ><br>51-75% Moderate repigmentation <br/ ><br>76-90% Marked repigmentation <br/ ><br>90% Excellent repigmentation <br/ ><br>Timepoint: To assess the difference in extent of repigmentation by the three different methods at 8 days,4 weeks, 8 weeks and 12 weeks of post treatment follow up in a given patient of stable vitiligo.