Electrofulguration- A novel technique in recipient site preparation in vitiligo surgery.
Not Applicable
- Conditions
- Health Condition 1: L80- Vitiligo
- Registration Number
- CTRI/2020/01/022671
- Lead Sponsor
- Department of Dermatology Venereology and Leprology PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Clinical diagnosis of segmental or non segmental vitiligo
2 independent patchesbof 3x 3 cm size each present symmetrically or unilaterally over the same part or a single patch ofvsize 6x6 cm
Stable leaions for more than 1 year
Disease is not responding to medical therapy for 12 weeks or residual patches post medical therapy
Exclusion Criteria
Pregnancy and lactation
History of unstable cardiac diseasevor pacemakers
Patients with active disease VIDA more than 1
History of hypertrophic scars or keloid
Skin infection
Patients with unrealistic expectations
History of bleeding disorders
Patients on anticoagulants
Immunosuppressed patients
Patients still in wash off period of therapy that is 4 weeks for topical and 12 weeks for systemic therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the percentage of patients achieving 75 percent repigmentation with respect to the two different methods at 24 weeks of follow up post treatmentTimepoint: 0 4 8 12 16 24 weeks
- Secondary Outcome Measures
Name Time Method To assess whether the extent of repigmentation has any correlation to the expression levels of growth factors which are SCF, bFGF, endothelin 1Timepoint: 0 4 8 12 16 24 weeks;To evaluate the repigmentation patterns of the lesions pre and post post procedure by dermoscopy and to ennumerate the dermatoscopic markers of repigmentation as well markers of success of the procedureTimepoint: 0 4 8 12 16 24 weeks