Heart Failure With Mildly Reduced Ejection Fraction Registry
- Conditions
- Heart Failure
- Registration Number
- NCT05603390
- Lead Sponsor
- Universitätsmedizin Mannheim
- Brief Summary
Heart failure (HF) affects about 1% of patients younger than 55 years, whereas the prevalence of HF increases \> 10% in patients with at least 70 years of age. Despite HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF), the clinical significance of HF with mildly reduced ejection fraction (HFmrEF) has gained more importance within the past years. Those patients are characterized by a left ventricular ejection fraction (LVEF) of 41-49%. However, within the current European guidelines, limited treatment recommendations in this subgroup of HF are yet available as a consequence of the limited number of studies in this field. The "Heart Failure With Mildly Reduced Ejection Fraction Registry" aims to characterize patients with HFmrEF and investigated the prognostic impact of interventional and pharmacological therapies in this subgroup of HF patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 2200
- Patients with HFmrEF (i.e., LVEF 41-49%)
- Patients with at least 18 years of age
- Patients younger than 18 years of age
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All-cause mortality 2 years. All-cause mortality
- Secondary Outcome Measures
Name Time Method Change of NT-pro BNP 2 years. Change of NT-pro BNP
Change of LVEF 2 years. Change of LVEF
Heart-failure related hospitalization 2 years. Heart-failure related hospitalization
Trial Locations
- Locations (1)
University Medical Centre Mannheim
🇩🇪Mannheim, Germany