Comparative study of Shigru (Moringa oleifera) stem bark and root bark lepa on dadru kushtha (dermatophytosis/ringworm)

Phase 2/3

Not yet recruiting

• Conditions: Atopic dermatitis, unspecified. Ayurveda Condition: DADRU-KUSHTHAH,

• Registration Number: CTRI/2023/05/052839
• Lead Sponsor: ALL INDIA INSTITUTE OF AYURVEDA

Brief Summary

*Shigru* (*Moringa olifera* Lam.) is a plant having multitude of uses be it therapeutic or nutraceuticals. The existing treatment protocol for *Dadru kushtha* (dermatophytosis) consists of various topical and oral steroids, antifungal creams and medication that gives temporary relief which on prolonged consumption causes hepatotoxicity and hormone related effects. Therefore in a recurrent condition like *Dadru* there is need for safe, efficacious, cost effective management thus a study on *shigru* is taken.  Acharaya Vangasena depicted in *kushtha chikitsa* to use *Shigru* root bark *lepa* as an effective remedy in *Dadru kushtha.* As the use of root bark may lead to the destruction of plant, it needs to be replaced by another part if possible. Hence considering similar activity in stem bark, this study emphasizes on the comparative analysis and clinical efficacy of stem bark *lepa*  with that of root bark *lepa.*

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-08
• Last Update Posted: 2023-05-17

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Patient with 21 to 60 years of age(in completed years) willing to participate in the study.
• Patient with classical sign and symptoms of Dadru kushtha with positive KOH mount test of skin sample.
• Patient belonging to either gender will be included in the study.

Exclusion Criteria

• Patient with known case of skin cancer, skin tuberculosis, scabies, psoriasis, contact dermatitis, candidiasis, malignant infection, secondary infections.
• Dadru kushtha chronicity more than 3 years C.
• Patient suffering from systemic illness under medications that could affect the study results.
• Pregnant and lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
More than 40 % improvement in clinical sign and symptoms i.e. kandu(itching), Raga(skin colour), Pidika(number of papules per mandala), Utsanna mandala(number of elevated circular patch, Utsanna mandala(size of elevated circular patch in cm) of Dadru kushtha at 7 days interval of 21 days of study.	assessment will be done at day 0,7,14,21 and follow up at day 31 and day 42

Secondary Outcome Measures

Name	Time	Method
Improvement in quality of life of patients assessed using DLQI at 7 days interval of 21 days of study.	Assessment will be done at day 0,7,14,21 and follow up at day 31 and day 42

Trial Locations

Locations (1)

All india institute of ayurveda; 🇮🇳 South, DELHI, India

All india institute of ayurveda

🇮🇳South, DELHI, India

DR ARCHANA KUMARI

Principal investigator

08700479820

archana.kumari.ak85@gmail.com