A Comparitive Study to Evaluate the Efficacy and Safety of Chlorthalidone with Losartan versus Amlodipine with Losartan in Patients With Primary Hypertensio
Phase 4
Completed
- Conditions
- Health Condition 1: I10- Essential (primary) hypertension
- Registration Number
- CTRI/2022/03/041375
- Lead Sponsor
- BMCRI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1.Patient willing to give written informed consent
2.Patients who are diagnosed to be having Stage 2 hypertension as per JNC 8 guidelines
Exclusion Criteria
1.Patients having comorbidities like Chronic kidney disease, Stroke , Congestive Heart Failure, Myocardial infarction , Coronary Artery Disease, Psychiatric Disorders, Suspected Secondary Hypertension (Eg. Renal artery stenosis, Cushingââ?¬•s syndrome )
2.Pregnant and Lactating mothers
3.Patients with hypersensitivity to the study medications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean reduction in systolic/diastolic blood pressure after 8 weeks of therapyTimepoint: Baseline , 4 weeks and 8 weeks
- Secondary Outcome Measures
Name Time Method Patients achieving Target Blood pressure of � 140/90 mmHg <br/ ><br>Timepoint: 8 weeks