Efficacy of oral tranexamic acid and topical triple combination cream in treatment of melasma
Phase 4
- Conditions
- Health Condition 1: L814- Other melanin hyperpigmentation
- Registration Number
- CTRI/2024/04/065382
- Lead Sponsor
- MOHAN H
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients willing to give informed consent
2. Patients of either gender aged more than 18 years
3. Patients willing for follow up
4. Patients with clinically diagnosed melasma
Exclusion Criteria
1. Patient not willing to give informed consent
2. Patient already on melasma treatment with topical therapy within 2 weeks.
3. Pregnant and lactating females.
4. History of coexisting endocrinopathies.
5. History of thrombosis, thromboembolic episodes and altered blood coagulation profile.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in melasma area and severity indexTimepoint: Change in melasma area and severity index at 4 weeks and 8 weeks
- Secondary Outcome Measures
Name Time Method Safety and tolerability parameters of study medicationsTimepoint: At 4 weeks and 8 weeks