Efficacy of two different injections in scar treatment

Conditions: Hypertrophic and keloid scars are pathological scars as a result of dermal injury and exhibit exuberant, indefinite growth of collagen during wound healing. Hypertrophic and keloid scars often cause symptoms such as hypersensitivity, pruritus or pain. Patients are often affected with major cosmetic, psychological and social consequesnce.
Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]

Registration Number: EUCTR2014-003216-37-NL

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Authorised-recruitment may be ongoing or finished

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

? Hypertrophic scar
Definition: Excessive overgrowth of dense collagen tissue, often red, pink, or purple in
appearance, at the site of a healed skin defect. It resembles a keloid but is usually
temporary, most often regresses without treatment, and remains confined to the site
of injury.( http://medical-dictionary.thefreedictionary.com/hypertrophic+scarring)
? Keloid scar
Definition: A nodular, firm, often linear mass of hypertrophic thickish scar tissue,
consisting of irregularly distributed bands of collagen; occurs in the dermis, usually
after trauma, surgery, burn, or a severe cutaneous disease. (http://medical
dictionary.thefreedictionary.com/keloid)
? = 18 years old

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 45
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

? Hypertrophic or keloid scar on ear and scalp
? Hypertrophic or keloid scar with a treatment history of radio-, brachy- or
cryotherapy, or steroid- or other intralesional therapies
? Allergy or intolerance to corticosteroids or Verapamil
? Pregnancy