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临床试验/CTRI/2025/03/082578
CTRI/2025/03/082578招募中不适用

Efficacy of velocity time integral and left ventricular end diastolic area using transthoracic echocardiographic for predicting hypotension induced by general anesthesia

Gandhi medical College and hamidia hosital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年3月28日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
40
试验地点
1
主要终点
To determine the predictive value of two transthoracic echocardiographic parameters, velocity time integral and left ventricular end diastolic area in predicting the occurrence of hypotension during intraoperative period upto 2 hours.

研究概览

简要总结

General anesthesia is essential for modern surgery, ensuring unconsciousness and pain relief during invasive procedures. However, it often leads to hypotension, which can cause severe complications like myocardial infarction, stroke, and renal failure. Hypotension during anesthesia results from factors such as vasodilation, reduced vascular resistance, and cardiac depression, highlighting the need for early risk identification and preventive measures. Transthoracic echocardiography (TTE) has become a vital tool for assessing cardiac function, offering real-time visualization of heart structures and blood flow. TTE-derived parameters like Velocity Time Integral (VTI), which measures stroke volume, and Left Ventricular End-Diastolic Area (LVEDA), indicating ventricular filling and function, are particularly useful for evaluating cardiac health. These parameters can help predict and manage anesthesia-induced hypotension, especially in non-cardiac patients, by enabling early risk detection and timely intervention. This study explores the potential of VTI and LVEDA as predictive markers for hypotension during general anesthesia, aiming to enhance perioperative care and patient safety through improved risk stratification and monitoring.

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • ASA 1, 2, BMI less than 28 posted for elective surgeries.

排除标准

  • Emergency surgeries with risk of aspiration, patient with cardiac disease history, pregnancy.

结局指标

主要结局

To determine the predictive value of two transthoracic echocardiographic parameters, velocity time integral and left ventricular end diastolic area in predicting the occurrence of hypotension during intraoperative period upto 2 hours.

时间窗: To determine the predictive value of two transthoracic echocardiographic parameters, velocity time integral and left ventricular end diastolic area in predicting the occurrence of hypotension during intraoperative period upto 2 hours

次要结局

  • To determine potential difference in predictive performance between VTI & LVEDA accross different surgical procedures & patient demography(Within Two hour of general anesthesia induction)

研究者

发起方
Gandhi medical College and hamidia hosital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Aseem Gargava

Gandhi Medical college

研究点 (1)

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