jRCT2080221755未知1 期
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY110140 in Healthy Japanese Male Subjects
适应症
试验速览
- 阶段
- 1 期
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- No limit 至 No limit（—）
- 性别
- Male
入选标准
- •[Inclusion Criteria]
- •Overtly healthy Japanese males (as determined by medical history and physical examination) who agree to use a reliable method of birth control during the study and for 3 months following the last dose of the investigational product.
- •Have a body mass index (BMI) of 18.5 to 29.9kg/m^2, inclusive, at the time of screening.
- •Have given written informed consent approved by Lilly and the ethical review board (ERB) governing the study site.
排除标准
- •[Exclusion Criteria]
- •Poor metabolizers of enzyme Cytochrome P450 2D6 (CYP2D6) (assessed at screening).
- •Have an abnormality in the 12-lead Electrocardiogram (ECG) at screening that, in the opinion of the investigator, increases the risks associated with participating in the study such as, a Bazett's corrected QT(QTcB) intercal >450 millisecounds (msec).
- •Have any lifetime history of a suicide attempt, or have suicidal ideation or, any suicidal behavior within the last month, or who are at significant risk to commit suicide, as judged by the investigator using the Columbia Suicide Severity Rating Scale (C-SSRS).
- •Are unsuitable (in the opinion of the investigator or sponsor) for inclusion in the study.
研究者
相似试验
终止
1 期
A study to evaluate safety and tolerability of GS -5801 in healthy subjectsHepatitis B VirusInfection - Other infectious diseasesOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colonACTRN12616001260415Gilead Sciences, Inc.70
撤回
1 期
A Study of ELVN-002 in Healthy Adult Volunteers: Part BNon-small Cell lung canceron-small Cell lung cancerCancer - Lung - Non small cellACTRN12623000431628Enliven Therapeutics, Inc.6
撤回
不适用
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Injection of ABT-110 in Healthy Volunteers and Subjects with Chronic Low Back Paichronic low back pain10028302NL-OMON36923Abbott30
已完成
1 期
A phase 1 clinical trial of BIL06v/Alhydrogel to evaluate the safety, tolerability, immunogenicity and anti-tumour activity and to determine the most effective dose of BIL06v/Alhydrogel to treat patients with advanced forms of solid cancersAdvanced Solid CancersCancer - Any cancerACTRN12618000838213Biosceptre (Aust) Pty Limited29
招募中
1 期
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of T7-010 in Healthy Participants.Autoimmune Diseases (Healthy Volunteers)2024-518440-20-00T7 Therapeutics Inc.32