Contingency Management for the Treatment of Co-Occurring Alcohol and Drug Misuse

Not Applicable

Completed

• Conditions: Co-Occurring Alcohol and Drug Misuse
• Interventions: Behavioral: CM for Alcohol; Behavioral: CM for drugs; Behavioral: CM for both substances; Behavioral: Non-Contingent group

• Registration Number: NCT02222389
• Lead Sponsor: Washington State University

Brief Summary

Contingency management (CM) is a type of treatment used in the substance abuse field. Patients' behaviors are rewarded for adherence to a treatment plan. As an approach to treatment, contingency management emerged from the behavior therapy traditions in mental health. By most evaluations, contingency management procedures produce one of the largest effect sizes out of all mental health and educational interventions.

The purpose of this study is to perform a randomized, controlled trial to evaluate the ability of a culturally-tailored contingency management (CM) intervention to increase alcohol and drug abstinence among American Indian (AI) tribal members from two rural reservations in the Northwest.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-07-22
• Study First Submitted QC: 2014-08-19
• Study First Posted: 2014-08-21
• Study Start: 2015-06-01
• Status Verified: 2018-09
• Primary Completion: 2018-09-10
• Study Completion: 2018-09-10
• Last Update Submitted: 2018-09-15
• Last Update Posted: 2018-09-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Self-identify race as American Indian (AI)
2. Are seeking alcohol dependence and drug abuse treatment at a participating reservation
3. Are age 18 or older
4. Meet criteria of DSM-IV diagnosis of current alcohol dependence
5. Current drug misuse
6. Are not pregnant or planning to become pregnant for the duration of the study
7. Are English speaking
8. Have the ability to provide written informed consent

Exclusion Criteria

1. Have significant risk of dangerous alcohol withdrawal, defined as a history of alcohol detoxification or seizure during the last 12 months AND expression of concern by the patient and/or healthcare provider
2. Meet criteria for DSM-IV diagnosis of drug dependence
3. Have significant risk of dangerous drug withdrawal and/or self-reported or medically documented severe withdrawal from drugs in the last 6 months
4. Have any medical or psychiatric condition, such as organic brain disorder, dementia, or psychotic disorder, that the Principal Investigator determines would compromise safe study participation
5. Are receiving drugs under the direction of a physician for pain management or another medical condition for which drug abstinence is contraindicated

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
CM for alcohol	CM for Alcohol	CM for alcohol
CM for drugs	CM for drugs	CM for drugs
CM for both substances	CM for both substances	CM for both substances
Non-Contingent group	Non-Contingent group	No CM for either substance, the Non-Contingent (NC) group

Primary Outcome Measures

Name	Time	Method
Biochemically verified alcohol and/or drug abstinence	24 weeks	At every study visit, urine samples will be collected and analyzed for ethyl glucuronide and drugs. This helps assess Contingency Management as a treatment for alcohol and/or drug dependence.

Secondary Outcome Measures

Name	Time	Method
Self- reported data on health behaviors	24 weeks	We will also collect secondary outcome data on health behaviors that frequently correlate with alcohol and drug misuse with the following measures: 1. The Timeline Follow Back will be used to assess daily number of cigarettes smoked.; 2. Brief HIV Risk Behavior Scale; 3. Veteran's Rand- 12; 4. Self-Report Services Utilization Assessment
Self- reported data on alcohol and drug use	24 weeks	Measures used for self-reported data on alcohol and drug use: 1. The Alcohol and Drug Timeline Follow Back (TLFB); 2. The Current Opioid Misuse Measure (COMM); 3. The Addiction Severity Index, Native American Version (ASI-NAV)
Other substance use	24 weeks	Amphetamine, methamphetamine, cocaine, and marijuana, will be measured by the same procedures described for urine tests of alcohol and drug metabolites.

Trial Locations

Locations (1)

Washington State University; 🇺🇸 Spokane, Washington, United States