Contingency Management for Opioid and Stimulant Use Disorders in Primary Care

Not Applicable

Recruiting

• Conditions: Opioid Use Disorder; Stimulant Use Disorder
• Interventions: Behavioral: Contingency Management

• Registration Number: NCT05288751
• Lead Sponsor: University of Minnesota

Brief Summary

Contingency management (CM) is a behavioral intervention that involves incentivizing participants for target behaviors in a clinical setting. When applied to the treatment of substance use disorders, it has demonstrated efficacy in reducing the number of urine toxicology screens positive for illicit substances and increased engagement in treatment programs. However, there is a need to translate CM treatment to primary care settings. This study will implement and assess a CM program for patients with opioid use disorder, with or without comorbid stimulant use disorder, initiating outpatient addiction medicine services at a family medicine residency clinic. Eligible patients will earn monetary incentives for attending addiction medicine appointments and abstaining from substances during outpatient treatment. Data gathered from this pilot program will be used to improve patient outcomes, treatment, and retention for persons receiving medications for opioid use disorder (MOUDs) in a primary care setting.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-03-10
• Study First Submitted QC: 2022-03-10
• Study First Posted: 2022-03-21
• Study Start: 2022-06-15
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-31
• Last Update Posted: 2024-11-04
• Primary Completion: 2025-05-29
• Study Completion: 2025-05-29

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• At least 18 years of age
• Diagnosis of Opioid Use Disorder and/or Stimulant Use Disorder
• Recently initiated medications for opioid use disorder (MOUDs) at Broadway Family Medicine (BFM), within 2 weeks of recruitment
• Have an active prescription for buprenorphine-naloxone (Suboxone)

Exclusion Criteria

• Prescription for an amphetamine would exclude patients from the abstinence-based CM, but they could participate in the attendance-only CM.
• Dementia, development disabilities, or cognitive functioning that is too low to participate in study measures, as determined by chart review and consultation with overseeing physician.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Attendance-only CM	Contingency Management	Patients in this arm complete an appointments with his or her primary care provider (PCP) or member of the PCP's microteam . These appointments must be initiated by the PCP/microteam in accordance with the patient's treatment plan for regular follow-up appointments.
Attendance + abstinence CM	Contingency Management	Patients who test stimulant-positive during the initial urine drug screen (UDS) at their intake visit will be invited to additionally enroll in the abstinence CM schedule. All of the attendance-only CM rules described previously will apply to patients in the attendance + abstinence program.

Primary Outcome Measures

Name	Time	Method
Preliminary efficacy of CM on clinical outcomes: Visit Frequency	30 days post-intervention	Number of completed clinical visits per patient during the CM program.
Feasibility of CM for OUD in primary care: Retention	30 days post-intervention	Of those patients who enroll in the intervention study, the percent that complete the CM intervention period.
Preliminary efficacy of CM on clinical outcomes: Urine toxicology	30 days post-intervention	Percentage of UDS results that are negative for stimulants during the CM intervention period.
Feasibility of CM for OUD in primary care: Recruitment	30 days post-intervention	percentage of patients invited to participate enroll in the treatment intervention.

Trial Locations

Locations (1)

University of Minnesota; 🇺🇸 Minneapolis, Minnesota, United States