The Mechanical Characterisation of Human Saphenous and Popliteal Vein
- Conditions
- Peripheral Vascular Diseases
- Registration Number
- NCT04016649
- Lead Sponsor
- University Hospital of Limerick
- Brief Summary
Non-interventional study aiming to ascertain the mechanical properties of human saphenous and popliteal vein tissue.
- Detailed Description
The aim of this study is to mechanically characterise saphenous and popliteal vein segments that have been deemed waste following varicose vein procedures, lower limb amputation and lower limb bypass surgery.
By characterising the stress-stretch relationship of the vein vessel wall, treatment techniques can be better understood. Mechanical device design can be bteer informed and the the suitability of vein as a conduit for bypass and AVF procedures can be assessed.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 50
- Male or Female patients aged 18 years or older
- Patients undergoing varicose vein procedures or;
- Patients undergoing lower limb amputation or;
- Patients undergoing lower limb bypass surgery
- Patients unable to give informed consent
- Seriously ill/unconscious patients
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The identification of vein tissue mechanical distension and stretching properties. 2 years Vein tissue will undergo inflation-extension testing and unilaxial testing. The vein tissue will be cross-sectioned and rings of venous tissue will be mechanically characterised according to the properties exhibited.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Limerick
🇮🇪Limerick, Ireland