The Mechanical Characterisation of Human Saphenous and Popliteal Vein
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The identification of vein tissue mechanical distension and stretching properties.
研究概览
简要总结
Non-interventional study aiming to ascertain the mechanical properties of human saphenous and popliteal vein tissue.
详细描述
The aim of this study is to mechanically characterise saphenous and popliteal vein segments that have been deemed waste following varicose vein procedures, lower limb amputation and lower limb bypass surgery.
By characterising the stress-stretch relationship of the vein vessel wall, treatment techniques can be better understood. Mechanical device design can be bteer informed and the the suitability of vein as a conduit for bypass and AVF procedures can be assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or Female patients aged 18 years or older
- •Patients undergoing varicose vein procedures or;
- •Patients undergoing lower limb amputation or;
- •Patients undergoing lower limb bypass surgery
排除标准
- •Patients unable to give informed consent
- •Seriously ill/unconscious patients
结局指标
主要结局
The identification of vein tissue mechanical distension and stretching properties.
时间窗: 2 years
Vein tissue will undergo inflation-extension testing and unilaxial testing. The vein tissue will be cross-sectioned and rings of venous tissue will be mechanically characterised according to the properties exhibited.
次要结局
未报告次要终点
研究者
Fiona Leahy
Professor Eamon Kavanagh Prinicipal Investigator
University Hospital of Limerick