Characterization of Mechanical Tissue Properties in Pancreas, Liver and Colon
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Young's modulus (stiffness) on fresh tissue
研究概览
简要总结
This pilot research trial studies characterization of mechanical tissue properties in patients with pancreatic, liver, or colon cancer. Mechanical properties and stiffness of the cancerous tissue may be correlated with the standard pathology report that describes the stage of the disease.
详细描述
PRIMARY OBJECTIVES:
I. To determine if our optical polarimeter device is able to measure tissue stiffness across several human cancer types ex vivo.
SECONDARY OBJECTIVES:
I. To describe the inter- and intra-tumor heterogeneity of tissue stiffness. II. To determine if the measurements made by the optical polarimeter device are non-destructive.
TERTIARY OBJECTIVES:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled for surgery to remove primary tumors in the pancreas, liver or colon and have not undergone any prior treatment
- •Ability to understand and the willingness to sign a written informed consent
排除标准
- •Pregnant women will not be consented
- •Patients that are unable to consent for surgery
- •Primary liver tumors with cirrhosis will be excluded from this study
结局指标
主要结局
Young's modulus (stiffness) on fresh tissue
时间窗: Up to 15 months
A portable optical fiber polarimetric sensor device to measure the Young's modulus in tissue samples will be used.
次要结局
未报告次要终点