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Clinical Trials/NCT00593229
NCT00593229TerminatedNot Applicable

An Observational Study of All Forms of Thrombotic Microangiopathy in Pediatric Patients

Northwell Health1 site in 1 country6 target enrollmentStarted: January 2007Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Terminated
Enrollment
6
Locations
1
Primary Endpoint
Determine genetic causes of TMA

Study Overview

Brief Summary

This registry will collect clinical data and store biosamples (seru, plasma, urine, and DNA) annually from pediatric patients with thrombotic mcroangiopathy

Detailed Description

Children age, 6 months - 18 years, are eligible if they have one of the following categories of thrombotic microangiopathy (TMA):(1) severe D+HUS; (2) non-familial atypical HUS; (3) familial atypical HUS; or (4) TTP

Patients are seen intially and annually thereafter

Biosamples are collected for storage annually.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Prospective

Eligibility Criteria

Ages
6 Months to 18 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Severe HUS, familial or non-familial atypical HUS, TTP

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Determine genetic causes of TMA

Time Frame: Ongoing

Determine epidemiology and outcomes of the various forms of TMA

Time Frame: Ongoing

Secondary Outcomes

  • Initiate clinical trials in TMA(In the future)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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