NCT00593229TerminatedNot Applicable
An Observational Study of All Forms of Thrombotic Microangiopathy in Pediatric Patients
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Northwell Health
- Enrollment
- 6
- Locations
- 1
- Primary Endpoint
- Determine genetic causes of TMA
Study Overview
Brief Summary
This registry will collect clinical data and store biosamples (seru, plasma, urine, and DNA) annually from pediatric patients with thrombotic mcroangiopathy
Detailed Description
Children age, 6 months - 18 years, are eligible if they have one of the following categories of thrombotic microangiopathy (TMA):(1) severe D+HUS; (2) non-familial atypical HUS; (3) familial atypical HUS; or (4) TTP
Patients are seen intially and annually thereafter
Biosamples are collected for storage annually.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 6 Months to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Severe HUS, familial or non-familial atypical HUS, TTP
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Determine genetic causes of TMA
Time Frame: Ongoing
Determine epidemiology and outcomes of the various forms of TMA
Time Frame: Ongoing
Secondary Outcomes
- Initiate clinical trials in TMA(In the future)
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Unknown
Not Applicable
Institutional Registry of Thromboembolic DiseaseThromboembolismPulmonary EmbolismVenous ThromboembolismNCT01372514Hospital Italiano de Buenos Aires4,500
Recruiting
Not Applicable
Development of a Clinical and Biological Database in Rectum CancerRectal NeoplasmsNCT04006951Institut du Cancer de Montpellier - Val d'Aurelle300
Recruiting
Not Applicable
Establishment of a Prospective Clinical-biological DatabaseSarcomaNCT04458792Institut du Cancer de Montpellier - Val d'Aurelle450
Recruiting
Not Applicable
Development of a Cinical and Biological Database in Ovarian, Fallopian Tube and Peritoneal CancersCarcinoma, Ovarian EpithelialFallopian Tube NeoplasmsPeritoneal NeoplasmsNCT03976999Institut du Cancer de Montpellier - Val d'Aurelle300
Completed
Not Applicable
HTRS TE Registry (ThromboEmbolism Registry)ThromboembolismNCT00266994Nationwide Children's Hospital2,760