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The Clinical Observation for Chinese Medicine and Moxibustion in the treatment of low testosterone Oligoasthenozoospermia

Phase 2
Conditions
male infertility
Registration Number
ITMCTR1900002676
Lead Sponsor
onghua Hospital Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria

(1) Those who meet the above diagnostic criteria at the same time;
(2) Aged 22 to 60 years old;
(3) The course of the disease is more than 6 months;
(4) Volunteer subjects;
(5) Stop other Chinese and Western medicines for treating oligozoospermia;
(6) TCM syndrome differentiation is a syndrome of kidney essence deficiency (refer to the relevant standards in the Medical Science of Integrated Traditional Chinese and Western Medicine).

Exclusion Criteria

(1) Congenital malformation obstruction, testicular atrophy, varicocele greater than II degrees;
(2) Those with obvious genital malformations and reproductive system infections;
(3) Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system;
(4) Mental illness or a patient with a clear genetic factor;
(5) Allergic constitution or allergy to the study drug;
(6) Those with a history of active infectious diseases;
(7) Those who are engaged in special occupations that have obvious impact on fertility (such as radiation, electric welding, etc.);
(8) extremely oligospermia and necrospermia disease patients, positive anti-sperm antibody patients, abnormal of semen liquefaction and another abnormal semen patient;
(9) Patients who are considered unsuitable for sexual life or treatment, or who have incomplete data affecting efficacy or safety judgment;
(10) The woman has a history of infertility-related diseases, and sexual life is not normal, retrograde ejaculation or no ejaculation, and another sexual dysfunction patient;
(11) Those who are taking anti-epileptic diseases and anti-tumor drugs that interfere with sperm production and vitality;
(12) Those who have taken spermatogenic drugs in the last 3 months.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
serum total testosterone;sperm non-progressive motility;semen volume;sperm progressive motility;sperm total motility;semen concentration;
Secondary Outcome Measures
NameTimeMethod
partial androgen deficiency in aging male scale;serum prolactin;serum luteinizing hormone;serum follicle stimulating hormone;serum estradiol;serum total testosterone;Chinese medicine clinical symptom scale;
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