GLP-1 receptor agonists as preventive treatment of diabetes after renal transplantation: a single-arm interventional clinical trial.Study 2: Patients on the waiting list for kidney transplantation.

Bellvitge University Hospital0 个研究点目标入组 20 人开始时间: 2023年9月8日最近更新: 2024年7月22日

适应症

试验速览

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•Patients on the RT waiting list, Over 18 years, Women of childbearing potential must use effective contraceptive measures during their participation in the study., With metabolic syndrome defined by 3 or more of the following criteria (National Cholesterol Education Program Adult Treatment Panel III guidelines (7) adjusted to the patient with chronic kidney disease: a) prediabetes determined by: ? fasting plasma glucose of 100-126 mg/dL (5.6-6.9 mmol/L), ? and/or impaired fasting glucose of <126 mg/dL (7 mmol/L) with 2-h plasma glucose after oral glucose of 140–200 mg/dL (7.8–11 mmol/L) ? and/or HbA1c 5.7-6.4%) b) obesity defined by BMI = 27 Kg/m2 c) triglycerides =150 mg/dL or under treatment d) Waist circumference greater than 101.6 cm (men) or 88.9 cm (women)

•Under 18 years of age,, previously diagnosed diabetes,, Hepatic Failure, history of pancreatitis (acute or chronic),, síndrome de neoplasia endocrina múltiple tipo 2 (MEN 2), personal or family history of medullary thyroid carcinoma (MTC),, pregnant or lactating women, moderate to severe pre-existing gastroparesis.

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