NCT05323370已完成不适用
Study of New Potential Biomarkers of Lymphangioleiomyomatosis: Determination of Cathepsin K, Cystatin C, Collagen Telopeptides and Chondroitin Sulfates
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- urine cathepsin K proteins levels
研究概览
简要总结
This is a physiopathological case-control, non-interventional, monocentric study of adult patients with lymphangioleiomyomatosis. The controls are patients followed in neurology at the CHU of Tours for a tuberous sclerosis complex without lymphangioleiomyomatosis, the healthy volunteers are women with neither pulmonary nor renal pathology and recruited at the clinical investigation centre of the CHU of Tours.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
urine cathepsin K proteins levels
时间窗: inclusion visit
comparison of urine cathepsin K protein levels in the 3 groups
urine cathepsin K activity
时间窗: inclusion visit
comparison of urine cathepsin K activity in the 3 groups
次要结局
- urinary quantity of cystatin C(inclusion visit)
- FEV1 measurement(inclusion visit)
- serum level of chondroitin sulphates(inclusion visit)
- urinary quantity C and N-telopeptides of type 1 collagen(inclusion visit)
- VEGF-D measurement(inclusion visit)
- T-score measurement(inclusion visit)
- renal angiolipomas(inclusion visit)
研究者
研究点 (1)
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