CTRI/2024/07/071493尚未招募4 期
Comparison Between Intravenous Versus Nebulized Routes For Administering Dexmedetomidine And Ketamine Combination To Assist Awake Fiberoptic Intubation A Prospective Randomised Double Blind Study
Maharana Bhupal Government Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年8月8日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Cough score (severity of cough) during awake fiberoptic intubation
研究概览
简要总结
We would like to compare Intravenous and Nebulized routes for giving Dexmedetomidine with Ketamine on intubating conditions during awake fiberoptic intubation in terms of cough score, intubating condition, Ramsay sedation score, hemodynamic parameters , side effects / complications if any. Kindly grant CTRI registration for our study as IV Dexmedetomidine with ketamine and Nebulized Dexmedetomidine are FDA approved drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with ASA physical status Grade I and II Patients undergoing elective surgery under general endotracheal anesthesia Patients with Mallampati Class I and II.
排除标准
- •Patient refusal Psychiatric patients Emergency surgery Patients with severe bradycardia /heart block Pregnant and lactating mothers Patients having known allergy to any drugs used in the study Patients on long-term opioids or sedative medications Patients contraindicated to nasal intubation such as grossly distorted airway anatomy ,URTI and bleeding disorders.
结局指标
主要结局
Cough score (severity of cough) during awake fiberoptic intubation
时间窗: Up to 2 Min after awake fiberoptic intubation
次要结局
- Intubating condition(Vocal cord position)
研究者
Dr Sandeep Sharma
R.N.T Medical College
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Comparison of three different methods- nebulisation with Dexmedetomidine, Inj Dexamethasone intravenously and intra-cuff Lignocaine, for the prevention of sore throat in the postoperative period for patients undergoing surgeries under general anaesthesia.CTRI/2025/09/095450SRM Medical College105
已完成
4 期
Comparison of two intravenous drugs(Dexmedetomidine with Ketamine and Dexmedetomidine with Fentanyl) for passing tube (Endotracheal tube) via nose with help of Instrument (fiber scope) in patients without anaesthesia (in awake patients)CTRI/2024/09/073684Maharana Bhupal Government Hospital64
招募中
4 期
To Compare The Efficacy Of Nebulized Dexmedetomidine Versus Normal Saline For Patients Comfort And Satisfaction During Diagnostic Upper Gastrointestinal EndoscopyCTRI/2024/09/073834Dr Reshma salim64
尚未招募
4 期
Comparing Two Intravenous Drugs to Prevent Surges in Blood pressure and Heart Rate During Skull Pin Placement in Brain Tumor Surgery.CTRI/2025/08/092888Sri Sathya Sai Institute of Higher Medical Sciences60
尚未招募
不适用
Comparing two medicines, Dexmedetomidine and fentanyl to help patients wake up and recover calmly and smoothly after general anaesthesiaCTRI/2026/02/104228Mahatma Gandhi Medical College and Hospital160