Internet-Based Interventions for MDD

Not Applicable

• Conditions: Depression; Medication Adherence
• Interventions: Drug: antidepressant treatment; Other: antidepressant treatment combined with Internet-based interventions

• Registration Number: NCT04684277
• Lead Sponsor: Peking University

Brief Summary

The acute and remission depression patients of 18-65 years old were recruited. At the time of enrollment, the demographic, symptomatic, neuropsychological and medication adherence data was collected. After the completion of the baseline assessment and examination, the patients were given antidepressant treatment or antidepressant treatment combined with Internet-based interventions. Clinical evaluation was performed at 1, 3 months (acute patients) and 6, 12 months (remission patients) after treatment, including the medication adherence, therapeutic efficacy, recurrence rate and functional rehabilitation. Through above work, this research is expected to provide clinicians with a set of Internet generalized technologies to improve the compliance and clinical outcomes of patients with depression, and to provide patients with treatment and management of the entire disease cycle.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-12-21
• Study First Submitted QC: 2020-12-21
• Study First Posted: 2020-12-24
• Status Verified: 2021-09
• Study Start: 2021-09-01
• Last Update Submitted: 2021-09-21
• Last Update Posted: 2021-09-22
• Primary Completion: 2022-12-31
• Study Completion: 2023-06-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 440

Inclusion Criteria

• age 18-65 years old, acute (HAMD17 > 17) and remission (HAMD17 < 8) depression

Exclusion Criteria

• other mental illnesses, serious somatic illnesses

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
antidepressant treatment	antidepressant treatment	recieve antidepressant treatment
antidepressant treatment combined with Internet-based interventions	antidepressant treatment combined with Internet-based interventions	recieve antidepressant treatment combined with Internet-based interventions

Primary Outcome Measures

Name	Time	Method
recurrence rate	12 months	The difference of recurrence rate between the two groups was compared
HAMD17 reduction ratio	3 months	The difference of HAMD17 reduction ratio between the two groups was compared

Trial Locations

Locations (1)

Yunai Su; 🇨🇳 Beijing, China