跳至主要内容
临床试验/CTRI/2021/08/035523
CTRI/2021/08/035523尚未招募4 期

Comparative evaluation of the combination of intravenous Ketamine Hydrochloride plus Dexmedetomidine Hydrochloride and Ketamine Hydrochloride plus Midazolam Hydrochloride in procedural sedation for short surgical procedures- A randomized controlled study.

Dr Seethal Ann Sunny1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年8月14日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
we expect that dexmedetomidine plus ketamine will provide adequate depth of anaesthesia and more stable hemodynamic variables.

研究概览

简要总结

This study is a prospective, double blinded randomised controlled study comparing the effect of intravenous ketamine hydrochloride plus dexmedetomidine hydrochloride and intravenous ketamine hydrochloride plus midazolam hydrochloride in procedural sedation for short surgical procedures.  different drug combinations have been used for sedation in short surgical procedures. Here we tried to compare two drug combinations and try to find out a superior combination which would provide adequate sedation, hemodynamic stability and less postoperative complications.

研究设计

研究类型
Interventional
分配方式
Other
盲法
Participant and Investigator Blinded

入排标准

年龄范围
20.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Consent to participate in study ASA physical Grade 1 and 2 Patients undergoing short surgical procedures.

排除标准

  • Patients refusal.
  • Pregnancy and lactating women.
  • History of any significant pulmonary, cardiovascular, neurological, hepatoreanal or metabolic disease.
  • chronic use or addiction to opiates or sedatives.

结局指标

主要结局

we expect that dexmedetomidine plus ketamine will provide adequate depth of anaesthesia and more stable hemodynamic variables.

时间窗: 20 weeks

次要结局

  • We expect dexmedetomidine plus ketamine to provide less incidence of postoperative complications(20 weeks)

研究者

发起方
Dr Seethal Ann Sunny
申办方类型
Other [self]

研究点 (1)

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