Optimization of antimicrobial therapy based on average creatinine-urea clearance in critically ill patients - A Pilot study
Not Applicable
- Conditions
- Health Condition 1: N17- Acute kidney failureHealth Condition 2: A00-B99- Certain infectious and parasitic diseasesHealth Condition 3: J00-J99- Diseases of the respiratory system
- Registration Number
- CTRI/2024/07/069831
- Lead Sponsor
- All India Institute of Medical Sciences, Raipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age 18-75 both sexes
Patients admitted to the critical care unit (CCU)
Expected to stay more than 24 hours in CCU
Receiving at least one antimicrobial agent having renal clearance
Patient randomized to the intervention arm giving consent to collect 8-hour urine for average creatinine-urea clearance estimation
Exclusion Criteria
Chronic Kidney disease (CKD)
AKI on CKD
Patient not on renal replacement therapy at the time of enrollment
Clinical suspicion for Rhabdomyolysis
Pregnancy or breastfeeding.
Patients enrolled in other interventional clinical trials simultaneously
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method