evaluation of Probiotic lozenges, fluoride Mouthwash and Xylitol gum on Streptococcus mutans
Not Applicable
- Conditions
- Dental caries.
- Registration Number
- IRCT20231127060200N1
- Lead Sponsor
- Rafsanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Proper oral hygiene (brush at least twice a day)
The presence of at least 6 healthy teeth in each jaw without caries or complex restorations and crowns
Exclusion Criteria
Suffering from any systemic disease
Use of any type of antibiotic and probiotic products during the last month
Fluoride therapy and use of fluoride or antibacterial mouthwash during the last two weeks
Using birth control pills and being pregnant
Use of orthodontic devices and brackets, fixed and mobile prosthesis
Presence of sensitivity to probiotic products or other elements in the study such as fluoride or xylitol
Suffering from rapidly progressive caries, acute periodontal and gum diseases.
smoking
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The average number of Streptococcus mutans colonies. Timepoint: Sampling of patients will be done before the intervention and also on the 2nd, 14th and 30th days after the intervention. Method of measurement: Sampling of saliva by non-stimulating method and culture.
- Secondary Outcome Measures
Name Time Method