Investigating the effect of consecutive treatment with antibiotics and probiotics in functional flatulence

Phase 3

Recruiting

• Conditions: Flatulence.; Flatulence; R14.3

• Registration Number: IRCT20230912059417N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Age between 18 and 70 years
Having functional flatulence (based on Rome III criteria based on history and risk symptoms and functional flatulence diagnostic criteria)
Abdominal flatulence feeling at least 3 days a month in the last 3 months
The first experience of flatulence is more than 6 months before the study
Informed written consent to participate in the study

Exclusion Criteria

Any history of chronic inflammatory disease or structural disease of the gastrointestinal tract
Any serious physical problem or disease such as inflammation or malignancy
Use of calcium channel blocking drugs in the last 3 months
Positive family history for colon cancer
Celiac disease
Any receipt of antibiotics or probiotics 8 weeks before the study
Pregnancy or breastfeeding
alcohol consumption

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bloating severity score. Timepoint: Before of the intervention, 2, 4, 6 and 8 weeks after the start of the study. Method of measurement: Questionnaire IBS- QOL.;Quality of life. Timepoint: Before of the intervention, 2, 4, 6 and 8 weeks after the start of the study. Method of measurement: Questionnaire IBS- QOL.