Effect of Probiotic in reducing urticaria and pruritus in people with chronic urticaria

Phase 1

Recruiting

• Conditions: Hives.; Urticaria, unspecified; L50.9

• Registration Number: IRCT20190825044613N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

For at least two days of week patients must have urticaria lesions and these lesions must remain for at least 6 weeks.
Age between 18 to 45 years old

Exclusion Criteria

Serious comorbidities (such as malignancies, mental illness, hepatitis, endocrine or other acute and chronic systemic diseases)
Taking any drug other than antihistamines
Patients with vasculitis
Patients with urticaria due to autoimmune diseases
A history of severe gastrointestinal diseases such as indigestion and malabsorption
Patients taking corticosterone for any reason
A history of asthma and allergies in the patients and their first degree relatives
Patients with severe mental problems

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Itching severity. Timepoint: first visit - 8 Week after treatment. Method of measurement: Questionnaire and visit.;Urticaria activity score over 7 days (UAS7). Timepoint: first visit -- 8 Week after treatment. Method of measurement: Questionnaire and visit.;Number of hives. Timepoint: first visit - 8 Week after treatment. Method of measurement: Questionnaire and visit.

Secondary Outcome Measures

Name	Time	Method
Quality of Life. Timepoint: first visit snd 8 Week after treatment. Method of measurement: dermatology Quality Life Index.;Complications. Timepoint: 8 Week after treatment. Method of measurement: interview.;Tolerance of treatment and satisfaction. Timepoint: 8 Week after treatment. Method of measurement: interview.