Role of blood cellular mechanism in severity of COVID-19
Not Applicable
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 2: B342- Coronavirus infection, unspecified
- Registration Number
- CTRI/2020/10/028488
- Lead Sponsor
- All India Institute of Medical Sciences Patna India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
COVID positive patients
Exclusion Criteria
Known autoimmune diseases or carcinoma
Pregnancy
History of severe systemic illness
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br/ ><br>Relationship between markers of NETosis (Myeloperoxidase, Elastase, Citrullinated histones and severity of COVID-19 <br/ ><br>Timepoint: Change in the clinical category of patient according to the severity
- Secondary Outcome Measures
Name Time Method <br/ ><br>1. Relationship between markers of NETosis and inflammatory markers <br/ ><br>2. Relationship between markers of NETosis and anti inflammatory markers <br/ ><br>3. Relationship between markers of NETosis and clinical biomarkers <br/ ><br>4. Relationship between markers of NETosis and mortalityTimepoint: Day 1 & Day of change in severity of disease