ong COVID in Childre

Recruiting

Conditions: 08.9 LONG COVID

Registration Number: DRKS00028523

Lead Sponsor: niversitätsklinik Jena

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 150

Inclusion Criteria

Consent to data collection and examination/archiving of biomaterials
-Boys and girls who meet diagnostic criteria for Long Covid:
Evidence of previous SARS-CoV-2 infection (pos. SARS-CoV-2 PCR test and/or pos. SARS-CoV-2 antibody and a definite contact with a person with proven SARS-CoV-2 infection).
and
Presence of one or more symptoms compatible with Long COVID persisting longer than 4 weeks after infection and/or setting new on after initial recovery
and
relevant impairment of activities of daily life
and
no evidence for other causes wich could explain symptoms

Exclusion Criteria

- Pregnancy
- Diagnosis of a disease that explains part of the symptoms and arose independently of the SARS CoV-2 infection.

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary objective: Characterization of Long COVID-19 according to clinical, laboratory, functional and psychological aspects. Correlation to measurable organ damage, influence on quality of life. <br>Main parameter: change in quality of life caused by Long COVID-19 in childhood and adolescence, measured with SF 12.

Secondary Outcome Measures

Name	Time	Method
Secondary objectives/questions: What clues to the pathogenesis of long covid-19 can be elicited? What is the course of the disease? Can diagnostic criteria be established, or refined? Correlation to comorbidities. Correlation of functional diagnostics and laboratory with symptoms/suffering. Identification of disease-specific biomarkers.<br>Secondary outcome measures:<br>Clinical, laboratory, functional, and psychological changes at initial presentation and 3-month follow-up.