Clinical features of COVID-19 in Pediatric Patients, long term effects
- Conditions
- Covid-19 in children
- Registration Number
- NL-OMON27723
- Lead Sponsor
- Amsterdam UMC, location AMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 120
Aged 0-17 years at COVID-19 diagnosis, AND
-Presented to an emergency or outpatient department of a Dutch hospital and/or admitted to hospital, AND
-Diagnosed with COVID-19 in his/her medical history, based on at least one positive real-time RT-PCR test on nasopharyngeal, oropharyngeal, sputum or fecal sample for SARS-CoV-2 OR fulfilled a clinical diagnosis of COVID-19, should testing of SARS-CoV-2 yield inconclusive results and/or if testing is no longer possible due to lack of reagents, AND
-Enrolled in the COPP study (Clinical features of COVID-19 in Pediatric Patients (23)), with specific consent to be approached for follow-up studies.
-Consent from guardians and/or patient is not received, or
-Consent for COPP study data access is not received
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -To describe potential pulmonary sequelae, in particular symptoms, the need for hospital care, at 6 to 12-months following a COVID-19 diagnosis among pediatric patients receiving care in the hospital or outpatient setting in the Netherlands.<br>-To determine risk factors for pulmonary sequelae among COVID-19 hospitalized and outpatient pediatric patients in the Netherlands.<br>
- Secondary Outcome Measures
Name Time Method -To describe lung function in the follow-up of children with COVID-19.<br>-To describe exhaled breath profiles in children with a history of COVID-19<br>-To assess the quality of life in children with a history of COVID-19.<br>-To describe CT abnormalities in patients with chronic respiratory complaints and/or pulmonary function test abnormalities and a history of COVID-19.<br><br>