NCT04840121已完成不适用
ADHESIORT - Personalizing Window of Implantation During Frozen Embryo Transfer
Clinique Ovo2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2021年3月24日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Determination of appropriate window of implantation
研究概览
简要总结
Embryo implantation is a crucial event in the establishment of a pregnancy. Although the clinical and culture conditions to obtain a "good quality" embryo are well advanced today, endometrial receptivity remains a major barrier in assisted reproductive techniques. Once a high-quality embryo is transferred, impaired uterine receptivity is believed to be one of the major reasons behind failure of the establishment of pregnancy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women between the ages of 18 to 40 inclusive at the time of oocyte retrieval
- •Prescription of a single frozen embryo transfer - substituted cycle protocol
- •Participant has at least 2 vitrified good quality blastocysts
排除标准
- •Women undergoing fertility preservation
- •Stage IV severe endometriosis
- •Severe malformation, adenomyosis or uterine anomaly including fibroids deforming the uterine cavity ≥ 5 cm
- •Positive results of screening for either participant or partner for HIV antibodies, Hepatitis B (other than surface antibodies present after vaccination) or Hepatitis C
结局指标
主要结局
Determination of appropriate window of implantation
时间窗: 14 days after embryo transfer
Comparison between standard frozen embryo transfer and personalized frozen embryo transfer using AdhesioRT to determine a successful window of implantation
次要结局
- Rate of clinical pregnancy(14 days after embryo transfer)
研究者
研究点 (2)
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