Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Device: Low-level laser therapy and training; Other: Training

• Registration Number: NCT01784432
• Lead Sponsor: Universidade Federal de Sao Carlos

Brief Summary

Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.

Detailed Description

This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2012-01
• Study Completion: 2012-09
• Study First Submitted: 2012-09-15
• Status Verified: 2013-02
• Study First Submitted QC: 2013-02-03
• Last Update Submitted: 2013-02-03
• Study First Posted: 2013-02-05
• Last Update Posted: 2013-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• healthy males aged between 18 and 28 years;
• body mass index (BMI) equal to or less than 26 kg/m2;
• moderated pattern of physical activity

Exclusion Criteria

• previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
• osseous or articular disorder in the lower limbs,
• cardiovascular system disorders,
• systemic disease, and
• taking prescription medicines or using dietary supplements such as muscle mass builders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Low-level laser therapy and training	Low-level laser therapy and training	Effects of low-level laser therapy on muscle performance during physical strength training and gene expression of muscle tissue.
Training without low-level laser therapy	Training	Effects of physical strength training without low-level laser therapy on muscle performance and gene expression of muscle tissue

Primary Outcome Measures

Name	Time	Method
Global gene expression by microarray analysis	12 weeks

Secondary Outcome Measures

Name	Time	Method
Muscle performance in leg press device	12 weeks
Muscle performance in isokinetic dynamometer	12 weeks

Trial Locations

Locations (1)

Federal University of São Carlos; 🇧🇷 São Carlos, São Paulo, Brazil