Prediction of Prognosis in Patients With Chronic Obstructive Pulmonary Disease With Respiratory Failure: A Comparison of Three Nutritional Assessment Methods
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Sponsor
- West China Hospital
- Enrollment
- 750
- Locations
- 1
- Primary Endpoint
- Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of in-hospital death
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This is a retrospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during January 2014 to March 2016 by review of medical records. The following variables will be retrospectively studied: age, sex, marriage, height, weight, respiratory rate, PaO2, PaCO2, nutritional risk screening 2002 (NRS 2002) score, ALB, short-term and long-term prognostic outcomes, and so on. The purpose of this study is to compare the predictive power of three widely used nutritional assessment methods (BMI, NRS 2002 and ALB) predicting the prognostic outcomes in a cohort of COPD patients with respiratory failure.
Investigators
Lu Xing
Principal Investigator, Master Degree
West China Hospital
Eligibility Criteria
Inclusion Criteria
- •Newly diagnosis of COPD at West China Hospital during January 2014 to March 2016
- •Partial pressure of O2 (PaO2) \< 60 mmHg and/or partial pressure of CO2 (PaCO2) \>50 mmHg
- •Age ≥ 18 years
- •Respiratory rates \> 23 bpm
Exclusion Criteria
- •Pregnancy or during lactation
- •Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems
- •Incomplete medical profiles
Outcomes
Primary Outcomes
Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of in-hospital death
Time Frame: up to 27 months
Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 1-year death after discharge
Time Frame: up to 27 months
Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 30-day readmission after discharge
Time Frame: up to 27 months
Secondary Outcomes
- Number of participants with 1-year death after discharge(up to 27 months)
- Number of participants with 30-day readmission after discharge(up to 27 months)
- Number of participants with in-hospital death(up to 27 months)
- Collection of Demographics (age, sex, marriage)(up to 27 months)