Clinical Characteristics and Outcome of Patients With COPD With Pneumonia

Completed

• Conditions: Pneumonia; Chronic Obstructive Pulmonary Disease
• Interventions: Other: No inervention

• Registration Number: NCT04966026
• Lead Sponsor: Peking University Third Hospital

Brief Summary

To identify the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) combined with community-acquired pneumonia (CAP) and the factors influencing clinical transition.

Detailed Description

To identify the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) combined with community-acquired pneumonia (CAP) and the factors influencing clinical transition.Compared to other chronic airway diseases, COPD patients can often have CAP in combination, but there is a lack of comparative studies between COPD patients with CAP and non-COPD patients with CAP.

Study Timeline

• Study Start: 2017-03-01
• Primary Completion: 2018-02-28
• Status Verified: 2018-05
• Study Completion: 2018-05-30
• Study First Submitted: 2021-07-04
• Study First Submitted QC: 2021-07-14
• Last Update Submitted: 2021-07-14
• Study First Posted: 2021-07-19
• Last Update Posted: 2021-07-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 143

Inclusion Criteria

1. CAP meets the diagnostic criteria published in 2016 Chinese CAP diagnosis and treatment guidelines; CPOPD and AECOPD meet the diagnostic criteria published in Chinese 2013 COPD diagnosis and treatment guidelines;
2. Age ≧ 40years.

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Exclusion Criteria

1. age <40years;
2. pregnancy;
3. positive for human immunodeficiency virus (HIV) antibodies;
4. suspected or confirmed tuberculosis or fungal infection of the lung.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
COPD combined with CAP inpatients	No inervention	(1) CAP meets the diagnostic criteria published in our 2016 CAP diagnosis and treatment guidelines; CPOPD and AECOPD meet the diagnostic criteria published in our 2013 COPD diagnosis and treatment guidelines; (2) age ≧ 18 years. Exclusion criteria: (1) age \<18 years; (2) pregnancy; (3) positive human immunodeficiency virus (HIV) antibody; (4) suspected or confirmed tuberculosis or fungal infection of the lung.

Primary Outcome Measures

Name	Time	Method
mortality rate	Day 28 from hospitalization	mortality rate

Secondary Outcome Measures

Name	Time	Method
number of days in ICU	through study completion, an average of 1 year	number of days in ICU
hospital fees	through study completion, an average of 1 year	hospital fees.
cause of using antimicrobial drugs	through study completion, an average of 1 year	Days of using antimicrobial drugs during hospitalization
Number of days in hospital	through study completion, an average of 1 year	Number of days in hospital
number of days on mechanical ventilation	through study completion, an average of 1 year	number of days on mechanical ventilation

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China